Collateral Circulation

1. Front Matter

   Pages i-xv

   PDF

2. Collateral Arterial Growth and Reactivity: Lessons from the Limb and Renal Blood Supply

   • Norman K. Hollenberg

   Pages 1-15

3. Development of the Vascular System of Organs and Tissues

   • Werner Risau

   Pages 17-28

4. Methods for Assessing Coronary Collateral Growth: Insights Into Mechanisms Responsible for Collateral Development

   • David V. DeFily, William M. Chilian

   Pages 29-40

5. Coronary Collateral Development: Concepts and Hypotheses

   • Wolfgang Schaper

   Pages 41-64

6. Collateral Vessel Development in the Porcine and Canine Heart

   • Jutta Schaper, Dorothee Weihrauch

   Pages 65-102

7. Angiogenesis in Porcine Hearts with Coronary Microembolization

   • Masahiro Mohri, Wolfgang Schaper

   Pages 103-121

8. The Role of Growth Factors During Development of A Collateral Circulation in the Porcine Heart

   • Hari S. Sharma, Wolfgang Schaper

   Pages 123-147

9. Functional Aspects of Collateral Development in Animal Models

   • Hitonobu Tomoike

   Pages 149-172

10. Effect of Exercise and Pharmacologic Interventions on Coronary Collateral Blood Flow

    • Robert J. Bache

    Pages 173-193

11. Function and Development of Coronary Collateral Vessels

    • John C. Longhurst, J. David Symons

    Pages 195-214

12. The Role of Growth Factors in Collateral Development

    • Ellis F. Unger

    Pages 215-231

13. Interactions of the Coronary and Collateral Circulations

    • Konrad W. Scheel, Howard Mass, James T. Gean

    Pages 233-260

14. Exercise Induced Coronary Collateral Development: A Comparison to Other Models of Myocardial Angiogenesis

    • Francis C. White, David M. Roth, M. Dan McKirnan, Susan M. Carroll, Colin M. Bloor

    Pages 261-289

15. Collateral Circulation of the Brain

    • Konstantin-A. Hossmann

    Pages 291-315

16. Limb Collaterals

    • Werner Schoop

    Pages 317-327

17. Neurohumoral and Pharmacologic Regulation of Collateral Perfusion

    • David G. Harrison

    Pages 329-343

18. Venous Level Collaterals in the Coronary System

    • Michael V. Cohen, James M. Downey

    Pages 345-366

19. Microvascular Collaterals in the Coronary Circulation

    • H. Fred Downey

    Pages 367-380

20. Collateral Development and Function in Man

    • Attilio Maseri, Luis Araujo, Maria Luisa Finocchiaro

    Pages 381-402

Collateral blood vessels develop by growth of pre or newly formed structures in almost all vascular provinces as a consequence of progressing stenosis of the main artery. These alternative routes of blood supply are potentially able to alter the course of vascular disease. Collateral development is a time consuming process, and arterial stenosis and occlusion often progress faster than growth of the alternative routes.
The authors' ultimate goal is to provide a better understanding of collateral growth in order to pave the way for improving the conditions for these potentially selfhealing processes. These were programmed by nature but have not been perfected, probably because defenses against arterial disease had not been put under the pressure of natural selection.

• angiogenesis
• blood vessel
• circulation
• heart
• morphology
• tissue
• vascular disease

• Department of Experimental Cardiology, Max-Planck-Institute, Bad Nauheim, F. R. Germany

  Wolfgang Schaper, Jutta Schaper

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