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Fundamentals of Evidence-Based Health Care and Translational Science

  • Book
  • © 2014

Overview

Authors:
  1. Francesco Chiappelli

    1. CHS 63-090, UCLA School of Dentistry, Los Angeles, USA

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  • Explains in depth how best to conduct comparative effectiveness research as a basis for making evidence-based decisions in health care

  • Covers compelling current issues and a variety of analytical tools

  • Designed as a ready pocketbook and instant reference for researchers, health care providers, students, and instructors in the field

  • User-friendly, with a readily accessible structure, format, and style

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xxvii
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  2. Fundamental Implications for Clinical Practice

    1. Front Matter

      Pages 1-1
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    2. Translational Effectiveness in the Context of Translational Science

      • Francesco Chiappelli
      Pages 3-31

    3. Comparative Effectiveness Analysis and Evidence-Based Decisions

      • Francesco Chiappelli
      Pages 33-64

    4. Methodology I: The Best Available Evidence

      • Francesco Chiappelli
      Pages 65-88

    5. Methodology II: Sampling and Assessment of the Evidence

      • Francesco Chiappelli
      Pages 89-119

    6. Methodology III: Systematic Evaluation of the Statistical Analysis: Data Analysis in Research Synthesis

      • Francesco Chiappelli
      Pages 121-154

  3. Optimizing Clinical Practice-Based Patient-Centered Outcomes Research

    1. Front Matter

      Pages 155-155
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    2. Getting and Understanding Data

      • Francesco Chiappelli
      Pages 157-199

    3. Obtaining Data

      • Francesco Chiappelli
      Pages 201-228

    4. Describing and Analyzing Data

      • Francesco Chiappelli
      Pages 229-267

    5. Translational Effectiveness Analysis

      • Francesco Chiappelli
      Pages 269-290

    6. Optimizing Clinical Outcomes by Individualizing Observations

      • Francesco Chiappelli
      Pages 291-309

    7. Evaluation in Patient-Centered Outcomes Research

      • Francesco Chiappelli
      Pages 311-323

    8. Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research

      • Francesco Chiappelli
      Pages 325-359

  4. Back Matter

    Pages 361-394
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Keywords

About this book

Comparative effectiveness research – the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options – is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing “complex” systematic reviews, “cumulative” meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.

Reviews

From the book reviews:

“This is a single-author reference on evidence-based practice and translational science by a well-recognized author in the field. … The intended audience includes clinical investigators, medical practitioners, and students and teachers in medical sciences (especially dentistry), clinical/basic research, statistics, epidemiology, and biostatistics. … This book is excellent. It is a valuable resource for gaining a basic understanding of evidence-based research and translational science and its practical application … .” (Bhavesh Barad, Doody’s Book Reviews, September, 2014)

Authors and Affiliations

  • CHS 63-090, UCLA School of Dentistry, Los Angeles, USA

    Francesco Chiappelli

About the author

Professor Francesco Chiappelli, Ph.D. has contributed extensively to the development of the field of evidence-based and comparative effectiveness decision-making in health care over the past several years through his teaching, research publications, and authorship of several book chapters and books. Professor Chiappelli is the founder and director of the International Forum on evidence-based decisions and comparative effectiveness research (IF-EBD-CER), and is the honorary president of the Brazilian Association for Evidence-based dentistry. He is a American Dental Association Champion of evidence-based dentistry, and he is listed as a Fulbright Specialists for his expertise in evidence-based and comparative effectiveness analysis in health care.

Bibliographic Information

  • Book Title: Fundamentals of Evidence-Based Health Care and Translational Science

  • Authors: Francesco Chiappelli

  • DOI: https://doi.org/10.1007/978-3-642-41857-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2014

  • Hardcover ISBN: 978-3-642-41856-3Published: 03 April 2014

  • Softcover ISBN: 978-3-662-52011-6Published: 23 August 2016

  • eBook ISBN: 978-3-642-41857-0Published: 18 March 2014

  • Edition Number: 1

  • Number of Pages: XXVII, 394

  • Number of Illustrations: 28 b/w illustrations, 29 illustrations in colour

  • Topics: Medicine/Public Health, general

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