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“This is the latest in a series of works summarizing clinical developments and research in critical care and emergency medicine. … Senior trainees in any critical discipline and practitioners are the intended audience for this work, which originates from an international group of authors and is edited by a leader in multidisciplinary critical care. … The topics it covers will be of benefit to practicing intensivists and academicians. … this is a good summary of applied research in the field.” (David J. Dries, Doody’s Review Service, October, 2012)