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Epidemiology and Quantitation of Environmental Risk in Humans from Radiation and Other Agents

  • Book
  • © 1985

Overview

Editors:
  1. Amleto Castellani

    1. Department for Environmental Protection and Health, ENEA, CRE, Casaccia, Rome, Italy

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Part of the book series: NATO ASI Subseries A: (ASIAS, volume 96)

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-ix
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  2. Radiation Carcinogenesis

    • Edward E. Pochin
    Pages 1-16

  3. Strategy of Assessment of Health Risks in Environmental and Occupational Health

    • Reinier L. Zielhuis
    Pages 17-31

  4. Choice of Comparison Groups in Environmental Studies and Dealing with Background Morbidity in Various Subpopulations

    • Olav Axelson
    Pages 33-45

  5. The Probability of Causation: An Approach to the Problem of Toxic Torts, Especially with Respect to Exposures to Ionizing Radiation

    • Seymour Jablon
    Pages 47-62

  6. The Carcinogenic Effects of Diagnostic and Therapeutic Irradiation

    • P. G. Smith
    Pages 63-91

  7. Dose-Response in Radiation Carcinogenesis: Animal Studies

    • David G. Hoel
    Pages 93-103

  8. Dose-Response in Radiation Carcinogenesis:Human Studies

    • David G. Hoel, Dale L. Preston
    Pages 105-122

  9. Fundamentals of Dosimetry and Microdosimetry and the Relative Biological Effectiveness of Ionizing Radiations

    • Albrecht M. Kellerer
    Pages 123-140

  10. Critical Review of Case-Control and Cohort Study Methodologies

    • P. G. Smith
    Pages 141-155

  11. In Vitro Malignant Transformation — A Multi-Stepped Process

    • J. Justin McCormick, Veronica M. Maher
    Pages 157-174

  12. Problems in Dose Response and Risk Assessment : The Example of Asbestos

    • Julian Peto
    Pages 175-185

  13. Role of DNA Damage and Repair in the Mutagenesis of Human Cells by Carcinogens

    • Veronica M. Maher, J. Justin McCormick
    Pages 187-203

  14. Variations in DNA Repair Among People

    • R. B. Setlow
    Pages 205-212

  15. Cancer-Prone Families: A Resource for Etiologic Studies

    • Mark H. Greene
    Pages 213-223

  16. The Role of Human RAS Proto-Oncogenes in Cancer

    • Steven R. Tronick, Alessandra Eva, Shiv Srivastava, Matthias Kraus, Yasuhito Yuasa, Stuart Aaronson
    Pages 225-233

  17. Hereditary and Familial Disorders Linking Cancer Proneness with Abnormal Carcinogen Response and Faulty DNA Metabolism

    • M. C. Paterson, N. E. Gentner, M. V. Middlestadt, R. Mirzayans, M. Weinfeld
    Pages 235-267

  18. Application of Statistical Methods to Experimental Radiation Studies and to Radiation Epidemiology

    • Albrecht M. Kellerer
    Pages 269-289

  19. Biological Monitoring Studies in Occupational and Environmental Health

    • Reinier L. Zielhuis
    Pages 291-306

  20. The Recognition of New Kinds of Occupational Toxicity

    • John A. H. Lee, Thomas L. Vaughan, Paula H. Diehr, Robin A. Haertle
    Pages 307-337
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Keywords

About this book

The identification and quantitation of environmental risk in humans is one of the main problems to be solved in order to improve the protection of individuals and of human populations against phys­ ical and chemical pollutants. Epidemiology plays a central role in the evaluation of health risk directly in human populations. In this volume are collected 33 lectures presented at the AS! course on "Epidemiology and quanti tat ion of environmental risk in humans from radiation and other agents: potential and limitations", sponsored by NATO and Italian Association of Radiobiology and or­ ganized by ENEA. The course has been devoted to a number of aspects of environ­ mental risk analysis and evaluation based on epidemiological in­ vestigation. Basic epidemiological concepts and methods have been reviewed. Fundamentals of dosimetry and microdosimetry were presented in re­ lation to the contribution of epidemiology in defining the dose­ effect relationships for radiation carcinogenesis and its relation with age, sex and ethnicity. The mechanisms of carcinogenesis as a multi-stage process were illustrated. One of the main topics was 'cancer epidemiology' and its cor­ relation with: - occupational and non-occupational exposure to ra­ diation - diagnostic and therapeutic irradiation - cancer proneness - hereditary and familiar diseases - abnormal response to carcino­ gens - environmental pollution in air and water - exposure to radon in mines and in building material - atomic bomb explosion - chemo­ therapy - dioxin and related compounds.

Editors and Affiliations

  • Department for Environmental Protection and Health, ENEA, CRE, Casaccia, Rome, Italy

    Amleto Castellani

Bibliographic Information

  • Book Title: Epidemiology and Quantitation of Environmental Risk in Humans from Radiation and Other Agents

  • Editors: Amleto Castellani

  • Series Title: NATO ASI Subseries A:

  • DOI: https://doi.org/10.1007/978-1-4615-9445-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1985

  • Softcover ISBN: 978-1-4615-9447-5Published: 29 April 2013

  • eBook ISBN: 978-1-4615-9445-1Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: IX, 584

  • Number of Illustrations: 14 b/w illustrations

  • Topics: Veterinary Medicine/Veterinary Science

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