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Materials - Biomaterials | Metal-on-Metal Bearings - A Clinical Practicum

Metal-on-Metal Bearings

A Clinical Practicum

Jones, Lynne C., Haggard, Warren O., Greenwald, A. Seth (Eds.)

2014, X, 200 p. 46 illus., 26 illus. in color.

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  • Presents an historical overview of the use of metal-on-metal articulations
  • Collects for the first time the information necessary to assess clinically and biologically relevant patient outcomes
  • Addresses the practical questions that are being raised by surgeons, researchers, and engineers
  • Features contributions by acknowledged leaders in their fields
  • Describes what the clinician needs to know in order to practice evidence-based medicine
  • Projects directions for clinical, biological, and biomechanical research efforts

This book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants. Metal-on-metal bearings were introduced and evaluated as an alternative to other bearing couples, particularly metal-on-polyethylene, due to their enhanced wear resistance as determined in laboratory testing. Initially, reports of short-term clinical outcomes were favorable and an increasing number of metal-on-metal prostheses were implanted. Subsequently, isolated case findings describing adverse tissue responses around the articulation became the harbinger of an increasing number of reports describing pseudotumors and other significant lymphocytic-based responses associated with metal-on-metal prostheses. Questions have been raised as to whether this is an implant, design, or patient-specific response. The reasons why some patients have a negative biological response and pathology while others do not remain to be determined, but tens of thousands of patients in the US,  the UK, and around the world are considered to be at risk. Leading researchers and clinicians describe the issues related to the nature of the biological and pathological responses and the protocols that should be followed to determine if an adverse response is occurring. This book is essential reading for researchers, engineers, and orthopaedic surgeons who are involved in the design, evaluation, and implantation of metal-on-metal prostheses.

  • Presents an historical overview of the use of metal-on-metal articulations
  • Collects for the first time the information necessary to assess clinically and biologically relevant patient outcomes
  • Addresses the practical questions that are being raised by surgeons, researchers, and engineers
  • Features contributions by acknowledged leaders in their fields
  • Describes what the clinician needs to know in order to practice evidence-based medicine
  • Projects directions for clinical, biological, and biomechanical research efforts

Content Level » Research

Keywords » ALVAL - Adverse Tissue Reaction - Arthroplasty - Bearing Surfaces Materials - Histology and Metal-on-Metal Bearings Response - Metal Reactivity Bearings Response - Metal Sensitivity Bearings Response - Metal-on-Metal - Metal-on-Metal Bearings Book - Metal-on-Metal Bearings Pseudotumor - Outcome Studies Metal-on-Metal Bearings - Pseudotumor - Total Joint Arthroplasty

Related subjects » Biomaterials - Biomedical Engineering - Molecular Medicine - Orthopedics - Special types of Materials - Surfaces, Interfaces, Thin Films, Corrosion, Coatings

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