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Bioinformatics of Human Proteomics

  • Book
  • © 2013

Overview

Editors:
  1. Xiangdong Wang

    1. , Medicine, Biomedical Research Center, Fudan University Zhongshan Hospital, Shang Hai, China, People's Republic

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  • Provides practical and useful designs and methodologies
  • Reports the viewpoints of internationally distinguished scholars in the field
  • Conclusions are based on rigorous data analysis ?
  • Includes supplementary material: sn.pub/extras

Part of the book series: Translational Bioinformatics (TRBIO, volume 3)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Clinical Bioinformatics in Human Proteomics Research

    • Duojiao Wu, Haihao Li, Xiangdong Wang
    Pages 1-15

  3. Proteomics Defines Protein Interaction Network of Signaling Pathways

    • Shitao Li
    Pages 17-38

  4. Protein Function Microarrays: Design, Use and Bioinformatic Analysis in Cancer Biomarker Discovery and Quantitation

    • Jessica Duarte, Jean-Michel Serufuri, Nicola Mulder, Jonathan Blackburn
    Pages 39-74

  5. Proteomics and Cancer Research

    • Elena Lopez Villar, William Chi-Shing Cho
    Pages 75-101

  6. Toward Development of Novel Peptide-Based Cancer Therapeutics: Computational Design and Experimental Evaluation

    • Elena Pirogova, Taghrid Istivan
    Pages 103-126

  7. Advances in Proteomic Methods

    • Xianyin Lai
    Pages 127-167

  8. Clinical and Biomedical Mass Spectrometry: New Frontiers in Drug Developments and Diagnosis

    • Ákos Végvári, Melinda Rezeli, David Erlinge, György Marko-Varga
    Pages 169-185

  9. Disease Biomarkers: Modelling MR Spectroscopy and Clinical Applications

    • Luis Martí-Bonmatí, A. Alberich-Bayarri
    Pages 187-205

  10. Processing of Mass Spectrometry Data in Clinical Applications

    • Dario Di Silvestre, Pietro Brunetti, Pier Luigi Mauri
    Pages 207-233

  11. Bioinformatics Approach for Finding Target Protein in Infectious Disease

    • Hemant Ritturaj Kushwaha, Indira Ghosh
    Pages 235-255

  12. Identification of Network Biomarkers for Cancer Diagnosis

    • Jiajia Chen, Luonan Chen, Bairong Shen
    Pages 257-275

  13. Software Development for Quantitative Proteomics Using Stable Isotope Labeling

    • Xin Huang, Shi-Jian Ding
    Pages 277-294

  14. Clinical Translation of Protein Biomarkers Integrated with Bioinformatics

    • Xu Yang, Juanjuan Zhou, Chaoqin Du
    Pages 295-308

  15. Proteomic Approaches for Urine Biomarker Discovery in Bladder Cancer

    • Ming-Hui Yang, Yu-Chang Tyan
    Pages 309-329

  16. Antibody Microarrays and Multiplexing

    • Jerry Zhou, Larissa Belov, Nicola Armstrong, Richard I. Christopherson
    Pages 331-359

  17. Proteomics in Anaesthesia and Intensive Care Medicine

    • Ornella Piazza, Giuseppe De Benedictis, Geremia F. Zito Marinosci
    Pages 361-376

  18. Erratum

    • Elena Pirogova, Taghrid Istivan
    Pages E1-E1

  19. Back Matter

    Pages 377-390
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Keywords

About this book

“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.

Editors and Affiliations

  • , Medicine, Biomedical Research Center, Fudan University Zhongshan Hospital, Shang Hai, China, People's Republic

    Xiangdong Wang

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