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Written by leading scientists who apply quantitative systems methodology in their biological research
Covers a broad range of methods with a proven record of application to a wide variety of biomedical research problems
Contains step-by-step instructions for implementing computational techniques, much like in a laboratory protocol
Addresses the caveats of applying the systems analysis to biology from the practical researcher’s standpoint
Offers uniquely broad coverage of quantitative methods that account for the complex structural organization in biological systems
The rapidly developing methods of systems biology can help investigators to make inference and predictions from their data that intuition alone would not discern; however, the difficulty lies in the broad knowledge of mathematics and engineering that seems to be required to even evaluate the applicability of the methods to the problem at hand. In Systems Biology, scientists who possess that mathematical knowledge and have applied it effectively to various biological problems contribute methods which reflect their experience, crystallized in a form very similar to typical biological laboratory protocols. In order to best aid researchers, the chapters supply the theory behind the method, its step-by-step implementation, and the pitfalls explained thoroughly and from the practical angle. As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.
Cutting-edge and easy to use, Systems Biology shatters the perceived insurmountable barrier between the laboratory and systems-biological research techniques.
Content Level »Research
Keywords »Biomedical research - Biomolecular systems - Cellular processes - Large scale systems - Spatial analysis - Termination - biology - genome - methodology - molecular biology