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  • Book
  • © 2005

Metabolome Analyses:

Strategies for Systems Biology

  • First of its kind to address metabolome analyses from a ‘systems’ perspective

  • Includes contributions from current leading scientists and practitioners in the field

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xxi
  2. Introduction

    • Seetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre
    Pages 1-7
  3. Towards Integrative Functional Genomics Using Yeast as a Reference Model

    • Juan I. Castrillo, Stephen G. Oliver
    Pages 9-29
  4. Metabolomics for the Assessment of Functional Diversity and Quality Traits in Plants

    • Robert D. Hall, C.H.Ric de Vos, Harrie A. Verhoeven, Raoul J. Bino
    Pages 31-44
  5. Metabolomics: A New Approach Towards Identifying Biomarkers and Therapeutic Targets in CNS Disorders

    • Rima Kaddurah-Daouk, Bruce S. Kristal, Mikhail Bogdanov, Wayne R. Matson, M. Flint Beal
    Pages 45-61
  6. Metabolite Profiling with GC-MS and LC-MS

    • Ralf Looser, Amo J. Krotzky, Richard N. Trethewey
    Pages 103-118
  7. The Application of Electrochemistry to Metabolic Profiling

    • David F. Meyer, Paul H. Gamache, Ian N. Acworth
    Pages 119-135
  8. Differential Metabolic Profiling for Biomarker Discovery

    • Haihong Zhou, Aaron B. Kantor, Christopher H. Becker
    Pages 137-157
  9. NMR-Based Metabonomics in Toxicology Research

    • Laura K. Schnackenberg, Richard D. Beger, Yvonne P. Dragan
    Pages 159-171
  10. Methodological Issues and Experimental Design Considerations in Metabolic Profile-Based Classifications

    • Bruce S. Kristal, Yevgeniya Shurubor, Ugo Paolucci, Wayne R. Matson
    Pages 173-194
  11. Modelling of Fungal Metabolism

    • Helga David, Jens Nielsen
    Pages 195-214
  12. Detailed Kinetic Models Using Metabolomics Data Sets

    • Jacky L. Snoep, Johann M. Rohwer
    Pages 215-242
  13. Metabolic Networks

    • Eivind Almaas, Zoltán N. Oltvai, Albert-László Barabási
    Pages 243-264
  14. Metabolic Networks from a Systems Perspective

    • Wolfram Weckwerth, Ralf Steuer
    Pages 265-289
  15. Parallel Metabolite and Transcript Profiling

    • Alisdair R. Fernie, Ewa Urbanczyk-Wochniak, Lothar Willmitzer
    Pages 291-306
  16. Fluxome Profiling in Microbes

    • Nicola Zamboni, Uwe Sauer
    Pages 307-322
  17. Targeted Drug Design and Metabolic Pathway Flux

    • László G. Boros, Wai-Nang Paul Lee
    Pages 323-335
  18. Metabonomics in the Pharmaceutical Industry

    • Eva M. Lenz, Rebecca Williams, Ian D. Wilson
    Pages 337-348

About this book

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems.

The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.

Editors and Affiliations

  • School of Chemistry, The University of Manchester, UK

    Seetharaman Vaidyanathan, Royston Goodacre

  • Pfizer, Chesterfield, USA

    George G. Harrigan

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access