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  • Book
  • © 2008

Legionella Pneumophila: Pathogenesis and Immunity

  • Dr. Friedman is a long-term expert in the field of Legionella and he has assembled a team of distinguished and internationally recognized leaders in the field to contribute chapters in their respective areas of expertise

Part of the book series: Infectious Agents and Pathogenesis (IAPA)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XVIII
  2. Legionella pneumophila Pathogenesis: Lessons Learned from Genomics

    • Christel Cazalet, Carmen Buchrieser
    Pages 1-31
  3. Iron Assimilation and Type II Protein Secretion

    • Nicholas P. Cianciotto
    Pages 33-48
  4. The Dot/Icm Type IVB Secretion System

    • Jason J. LeBlanc, Joseph P. Vogel
    Pages 49-63
  5. Legionella in the Environment

    • Barry S. Fields
    Pages 85-94
  6. Regulation of the Legionella pneumophila Life Cycle

    • Rachel L. Edwards, Michele S. Swanson
    Pages 95-111
  7. Microbial Physiology

    • Paul S. Hoffman
    Pages 113-131
  8. Legionella pneumophila:Innate and Adaptive Immunity

    • Paul Hoffman, Herman Friedman, Mauro Bendinelli
    Pages 151-171
  9. Nonspecific Stimulation of Immunity Against Legionella

    • James Rogers, Amal Hakki, Herman Friedman
    Pages 173-183
  10. Interaction of Legionella pneumophila with Amoeba

    • Maélle Molmeret, Marina Santic, Yousef Abu Kwaik
    Pages 185-202
  11. Back Matter

    Pages 203-207

About this book

Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been new developments in this field including the publication of three whole genome sequences, the discovery of a developmental cycle and novel cyst-like highly infectious form, and the bacteria have been used as a probe for macrophage cellular function to unravel fundamental new knowledge in the area of cellular biology. Legionella has also become a model system for the study of innate as well as adaptive immunity. Information on Legionella continues to increase in the U.S. and abroad. Columbia University has started the first Legionella Genome Project with a multi-million dollar grant from the NIH. In addition, The European Working Group for Legionella infections was formed in 1986. Members are scientists with an interest in improving knowledge and information on the clinical and environmental aspects of legionnaires' disease through developments in diagnosis, management and treatment of the disease. The volume brings together all of the lastest research on this pathogen, the interest in which is rapidly growing.

Reviews

From the reviews:

"This small book … starts with information on the bacterial genome and ends with the review of an effective immune response to infection. This book will serve to update the scientific and medical community with information that will allow for the rapid detection and treatment of … infections. … The audience for this book includes clinicians, laboratory personnel, and scientists … . This compact reference full of good information … is easy to read and allows for quick retrieval of desired information." (Rebecca T. Horvat, Doody’s Review Service, August, 2008)

Authors and Affiliations

  • Department of Microbiology Medicine, Division of Infectious Diseases and International Health, UVA Health System, University of Virginia, Charlottesville, USA

    Paul Hoffman

  • College of Medicine, University of South Florida, Tampa, USA

    Herman Friedman

  • University of Pisa, Italy

    Mauro Bendinelli

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access