Developmental Biology

1. Front Matter

   Pages i-ix

   PDF

2. Development: Organisms Construct and Organize Themselves on the Basis of Inherited Information

   • Werner A. Müller

   Pages 1-8

3. Basic Stages, Principles, and Terms of Developmental Biology

   • Werner A. Müller

   Pages 9-20

4. Model Organisms in Developmental Biology

   • Werner A. Müller

   Pages 21-121

5. Comparative Review: The Phylotypic Stage of Vertebrates, Common versus Distinct Features, and Aspects of Evolution

   • Werner A. Müller

   Pages 122-136

6. The Egg Cell and the Sperm Get a Dowry

   • Werner A. Müller

   Pages 137-145

7. The Start: Fertilization and Activation of the Egg

   • Werner A. Müller

   Pages 146-155

8. Precisely Patterned Cleavage Divisions Are Driven by an Oscillator

   • Werner A. Müller

   Pages 156-159

9. Determination: Cells Are Programmed and Committed to Their Fates

   • Werner A. Müller

   Pages 160-164

10. Epigenetic Pattern Formation: New Patterns Are Created During Development

    • Werner A. Müller

    Pages 165-201

11. Differentiation Is Based upon Differential Gene Expression that Is Programmed during Determination

    • Werner A. Müller

    Pages 202-221

12. Cell Differentiation Frequently Is Irreversible and Causes Cell Death; Early Cell Death Can Be Programmed

    • Werner A. Müller

    Pages 222-227

13. Animal Morphogenesis Is Shaped Actively by Adhesion and Cell Migration

    • Werner A. Müller

    Pages 228-234

14. Cell Journeys: Even Germ Cells and Cells of the Peripheral Nervous System Originate from Emigrant Precursors

    • Werner A. Müller

    Pages 235-241

15. Development of the Nervous System: Cell Migration, Pathfinding, and Self-Organization

    • Werner A. Müller

    Pages 242-256

16. Heart and Blood Vessels: Divergent Developmental Roads but One System in the End

    • Werner A. Müller

    Pages 257-262

17. Stem Cells Enable Continuous Growth and Renewal

    • Werner A. Müller

    Pages 263-273

18. Signal Molecules Control Development and Growth

    • Werner A. Müller

    Pages 274-281

19. Cancer Comes from Disturbed Growth and Differentiation Control

    • Werner A. Müller

    Pages 282-288

20. Metamorphosis: A “Second Embryogenesis” Creates a Second Phenotype

    • Werner A. Müller

    Pages 289-300

No field of contemporary biomedical science has been more revolutionized by the techniques of molecular biology than developmental biology. This is an outstanding concise introduction to developmental biology that takes a contemporary approach to describing the complex process that transforms an egg into an adult organism. The book features exceptionally clear two-color illustrations, and is designed for use in both undergraduate and graduate level courses. The book is especially noteworthy for its treatment of development in model organisms, whose contributions to developmental biology were recognized in the 1995 Nobel Prize for physiology and medicine.

• Regeneration
• Vertebrate
• development
• developmental biology
• gene expression
• nervous system
• phenotype

• Zoologisches Institut—Physiologie, University of Heidelberg, Heidelberg, Germany

  Werner A. Müller

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