Aging of Organisms

1. Front Matter

   Pages i-ix

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2. Yeast Longevity and Aging

   • S. Michal Jazwinski

   Pages 1-30

3. Aging and Longevity in the Filamentous Fungus Podospora anserina

   • Heinz D. Osiewacz

   Pages 31-53

4. Genetic, Metabolic and Environmental Factors Associated with Aging in Plants

   • Karin Krupinska, Jon Falk, Klaus Humbeck

   Pages 55-78

5. Aging in Sponges

   • Heinz C. Schröder, Matthias Wiens, Werner E. G. Müller

   Pages 79-98

6. Aging and Environmental Conditions in Insects

   • Klaus-Günter Collatz

   Pages 99-123

7. Genetics of Aging in Drosophila

   • Linda Partridge, Scott D. Pletcher

   Pages 125-161

8. Aging in C. elegans

   • Anders Olsen, James N. Sampayo, Gordon J. Lithgow

   Pages 163-199

9. Aging in Birds

   • Donna J. Holmes

   Pages 201-219

10. Exploring the Mechanism of Aging Using Rodent Models

    • Yuji Ikeno, Holly Van Remmen

    Pages 221-246

11. Human Aging and Longevity: Genetic Aspects

    • Holger Hoehn, Armin Renner

    Pages 247-269

12. Back Matter

    Pages 271-276

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Biological aging as the time-depending general decline of biological systems associated with a progressively increasing mortality risk is a general phenomenom of great significance. The underlying processes are very complex and depending on genetic and environment factors. These factors encode or affect a network of interconnected cellular pathways. In no system this network has been deciphered in greater detail. However, the strategy of studying various biological systems has let to the identification of pathways and specific modules and makes it obvious that aging is the result of different overlapping mechanisms and pathways. Some of these appear to be conserved ("public") among species, others are specific or "private" and only of significance in one or a few organisms. This volume in the series on "Biology of aging and its modulation" specifically focuses on organismic aging. The book covers research on organisms from lower to higher complexity representing examples from very diverse taxa like photosynthetic plants, fungi, sponges, nematodes, flies, birds and mammals. Such a broad treatise of this complex topic provides a comprehensive "flavor" about the current issues dealt with in this rapidly growing scientific discipline.

• Drosophila
• aging
• cell
• environment
• fungi
• genetics
• insects
• yeast

• J.W. Goethe University, Frankfurt, Germany

  Heinz D. Osiewacz

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