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Mechanical Stretch and Cytokines

  • Book
  • © 2012

Overview

Editors:
  1. Andre Kamkin

    1. Dept. Fundamental &, Applied Physiology, Russian State Medical University, Moskva, Russian Federation

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  2. Irina Kiseleva

    1. , Department of Fundamental and Applied Ph, Russian State Medical University, Moscow, Russian Federation

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • This Volume demonstrates how mechanical stretch enhances cytokines production in different cells
  • It describes how cytokines influence tissues and cells on a background of a mechanical stretching
  • It provides a wide description of various signaling pathways, which employ cytokines and mechanotrasduction
  • One book brings together a comprehensive outline of modern vision of the role of cytokines in mechanotransduction

Part of the book series: Mechanosensitivity in Cells and Tissues (MECT, volume 5)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xv
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  2. Cytokine System

    • Andrey S. Simbirtsev, Ivan G. Kozlov
    Pages 1-33

  3. Mechanical Stretching of Cells of Different Tissues: The Role of Mediators of Innate Immunity

    • Leonid V. Kovalchuk, Marina V. Khoreva, Anna Nikonova, Viktor E. Kazanski, Ilya Lozinsky, Irina N. D’iakonova et al.
    Pages 35-58

  4. Mechanosensitive Pro-inflammatory Gene Expression in Vascular Cells

    • Marco Cattaruzza, Andreas H. Wagner, Markus Hecker
    Pages 59-86

  5. Cytokines, Heart and Calcium Current in Sepsis

    • Milan Stengl, Miroslav Prucha, Martin Matejovic
    Pages 87-106

  6. The Role of Proinflammatory Cytokines in Regulation of Cardiac Bioelectrical Activity: Link to Mechanoelectrical Feedback

    • Vlad S. Kuzmin, Denis V. Abramochkin, Vadim M. Mitrochin, Bo Tian, Ekaterina Yu. Makarenko, Leonid V. Kovalchuk et al.
    Pages 107-153

  7. An Anti-inflammatory Cytokine Interleukin-13: Physiological Role in the Heart and Mechanoelectrical Feedback

    • Denis V. Abramochkin, Ekaterina Yu. Makarenko, Vadim M. Mitrochin, Bo Tian, Vlad S. Kuzmin, Leonid Kalugin et al.
    Pages 155-164

  8. Mechanical Stretch and Cytokine Synthesis in Pulmonary Endothelial Cells

    • Satoru Ito, Yoshinori Hasegawa
    Pages 165-187

  9. Implications of Cytokines in Cochlear Pathophysiology

    • Keiji Tabuchi, Akira Hara
    Pages 189-199

  10. Primary Cilia are Mechanosensory Organelles with Chemosensory Roles

    • Brian S. Muntean, Xingjian Jin, Surya M. Nauli
    Pages 201-222

  11. Identification of Mechanosensitive Genes in Chondrocytes and Osteoblasts and Their Role in OA Pathogenesis

    • Yves Henrotin, Laurence Pesesse, Christelle Sanchez
    Pages 223-233

  12. Back Matter

    Pages 235-236
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Keywords

About this book

This book presents the latest findings in the field of investigation of molecular mechanisms of mechanical stretch and the role of cytokines in response of different tissues to it. On the one hand this Volume demonstrates how mechanical stretch enhances cytokines production. It describes how cytokines influence tissues and cells on a background of a mechanical stretching. It provides a description of how cells in different tissues are activated by stretch and cytokines via various signaling pathways, and how they change their gene expression. The book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Knowledge of biomechanics, and mechanisms which underlie it on molecular, cellular and tissue, is necessary for understanding of the normal functioning of living organisms and allows to predict changes, which arise due to alterations of their environment.

Editors and Affiliations

  • Dept. Fundamental &, Applied Physiology, Russian State Medical University, Moskva, Russian Federation

    Andre Kamkin

  • , Department of Fundamental and Applied Ph, Russian State Medical University, Moscow, Russian Federation

    Irina Kiseleva

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