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Cell Therapy

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. Yasuo Ikeda

    1. Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

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  2. Jun-ichi Hata

    1. Department of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

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  3. Shigeo Koyasu

    1. Department of Microbiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

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  4. Yutaka Kawakami

    1. Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

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  5. Yutaka Hattori

    1. Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

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  • Written by 21 selected scientists from all over the world, this book provides up-to-date information on stem cell research and its clinical application
  • The topics included are immunotherapy for malignant diseases, hematopoietic stem cells biology and clinical application, and international collaboration in hematopoietic stem cell transplantation

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Table of contents (21 papers)

  1. Front Matter

    Pages I-XVI
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  2. Immunotherapy for Malignant Diseases

    1. Front Matter

      Pages 1-1
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    2. Breaking Immunological Tolerance to Tumor Cells as a Novel Immunotherapy for Cancer

      • Shimon Sakaguchi, Takeshi Takahashi, Jun Shimizu
      Pages 3-13

    3. SART1 Gene Encoding Squamous Cell Carcinoma Antigen Recognized by Cytotoxic T Lymphocytes

      • Kyogo Itoh, Shigeki Shichijo, Yoshiko Inoue, Akihiro Hayashi, Uhi Toh, Hideaki Yamana
      Pages 15-28

    4. Adoptive Immunotherapy of Human Diseases with Antigen-Specific T-Cell Clones

      • Stanley R. Riddell, Edus H. Warren, Deborah Lewinsohn, Scott Brodie, Rici De Fries, Lawrence Corey et al.
      Pages 29-44

    5. Adoptive Transfer of Polyclonal, EBV-Specific Cytotoxic T-Cell Lines for the Prevention and Treatment of EBV-Associated Malignancies

      • Cliona M. Rooney, M. Helen Huls, Richard A. Rochester, Malcolm K. Brenner, Helen E. Heslop
      Pages 45-60

    6. Processing of Antigens by Dendritic Cells: Nature’s Adjuvant

      • Kayo Inaba
      Pages 61-68

    7. Immunotherapy of Melanoma Using Dendritic Cells

      • Frank O. Nestle
      Pages 69-76

    8. Immunotherapy of Melanoma Using T-Cell-Defined Antigens

      • Yutaka Kawakami
      Pages 77-92

  3. Hematopoietic Stem Cells Biology and Clinical Application

    1. Front Matter

      Pages 93-93
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    2. Isolation and Characterization of CD34-Low/Negative Mouse Hematopoietic Stem Cells

      • Hiromitsu Nakauchi, Masatake Osawa, Kazuhiro Sudo, Hideo Ema
      Pages 95-103

    3. Ex Vivo Expansion of Human Hematopoietic Stem Cells

      • Tatsutoshi Nakahata, Ming-Jiang Xu, Takahiro Ueda, Sahoko Matsuoka, Mamoru Ito, Kohichiro Tsuji
      Pages 105-106

    4. Notch in Hematopoiesis: Cell Fate Decisions and Self-Renewal of Progenitors

      • Laurie A. Milner, Anna Bigas
      Pages 107-121

    5. Molecular Genetics of Acute Promyelocytic Leukemia: A Rationale for “Transcription Therapy” for Cancer

      • Pier Paolo Pandolfi
      Pages 123-132

    6. A Novel Acute Promyelocytic Leukemia Model: From Cell to Murine System

      • Masahiro Kizaki
      Pages 133-142

    7. Phase 1 Trial of Retroviral-Mediated Transfer of the Human MDR-1 in Patients Undergoing High-Dose Chemotherapy and Autologous Stem Cell Transplantation

      • Charles Hesdorffer, Janet Ayello, Maureen Ward, Andreas Kaubisch, Arthur Bank, Karen Antman
      Pages 143-157

    8. Basic Studies Toward Hematopoietic Stem Cell Gene Therapy

      • Yutaka Hanazono, Cynthia E. Dunbar, Robert E. Donahue, Ikunoshin Kato, Yasuji Ueda, Mamoru Hasegawa et al.
      Pages 159-169

    9. Ex Vivo Expansion of Hematopoietic Cells

      • Ian McNiece, Roy Jones, Pablo Cagnoni, Scott Bearman, Yago Nieto, Elizabeth J. Shpall
      Pages 171-183

    10. Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy

      • Sergio A. Giralt
      Pages 185-193

    11. Ex Vivo Expansion of Human Cord Blood Stem Cells and Genetic Manipulation

      • Kiyoshi Ando, Hiroshi Kawada, Takashi Shimizu, Takashi Tsuji, Yoshihiko Nakamura, Minoru Kimura et al.
      Pages 195-204
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Keywords

About this book

Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International Symposium of Keio University for Life Sciences and Medicine on Cell Therapy.
All chapters include innovative basic research for clinical application: immunotherapy, cancer vaccination, molecular biology of hematopoietic stem cells, stem cell processing, and gene therapy.
The book is divided into three parts: Immunotherapy for malignant diseases; Hematopoietic stem cell biology and clinical application; and International collaboration in hematopoietic stem cell transplantation. Included in the third part is information on bone marrow registries from around the world.
The book thus presents up-to-date information on biological and clinical aspects of treatment, with insight into the future of cell therapy.

Editors and Affiliations

  • Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Yasuo Ikeda, Yutaka Hattori

  • Department of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Jun-ichi Hata

  • Department of Microbiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Shigeo Koyasu

  • Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Yutaka Kawakami

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