Logo - springer
Slogan - springer

Life Sciences - Cell Biology | Intracellular Antibodies - Development and Applications

Intracellular Antibodies

Development and Applications

Cattaneo, Antonino, Biocca, Silvia (Eds.)

Jointly published with Landes Bioscience, Georgetown, USA

Softcover reprint of the original 1st ed. 1997, XIII, 196 p.

Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$69.99

(net) price for USA

ISBN 978-3-662-07992-8

digitally watermarked, no DRM

Included Format: PDF

download immediately after purchase


learn more about Springer eBooks

add to marked items

Softcover
Information

Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$99.00

(net) price for USA

ISBN 978-3-662-07994-2

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

  • About this book

  • This is the first book to describe how antibodies can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus).
Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

Content Level » Professional/practitioner

Keywords » Antik├Ârper - Expression - Genexpression - Immunologie - antibody - biotechnology - diseases - gene - gene expression - gene therapy - immunology - infectious disease - protein - resistance - virus

Related subjects » Biotechnology - Cell Biology - Immunology - Molecular Medicine

Table of contents 

1. Intracellular and Intercellular Immunization.- 2. Current Methods for Genotypic and Phenotypic Knock-Outs in Mammalian Cells.- 3. Recombinant Antibodies for Ectopic Expression.- 4. Assembly and Folding of Antibodies in Natural and Artificial Environments.- 5. Protein Sequence Motifs Involved in Intracellular Trafficking.- 6. Intercellular Immunization.- 7. Intracellular Immunization.- 8. Gene Therapy and Research Applications of Intrabodies for Human Infectious Diseases.- 9. Plantibodies: Immunomodulation and Immunotherapeutic Potential.- 10. From Phage Libraries to Intracellular Immunization.- 11. Perspectives and Conclusions.

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Cell Biology.