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Intracellular Antibodies

Development and Applications

  • Book
  • © 1997

Overview

  • This is the first book to describe how antibodies can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus).

Part of the book series: Biotechnology Intelligence Unit (BIOIU)

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Table of contents (11 chapters)

Keywords

About this book

Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

Editors and Affiliations

  • Biophysics Sector, International School for Advanced Studies (SISSA), Trieste, Italy

    Antonino Cattaneo

  • Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata”, Roma, Italy

    Silvia Biocca

Bibliographic Information

  • Book Title: Intracellular Antibodies

  • Book Subtitle: Development and Applications

  • Editors: Antonino Cattaneo, Silvia Biocca

  • Series Title: Biotechnology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-07992-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Softcover ISBN: 978-3-662-07994-2Published: 03 December 2012

  • eBook ISBN: 978-3-662-07992-8Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: XIII, 196

  • Number of Illustrations: 20 b/w illustrations

  • Additional Information: Jointly published with Landes Bioscience, Georgetown, USA

  • Topics: Cell Biology, Immunology, Biotechnology, Molecular Medicine

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