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Signaling Through the Cell Matrix

  • Book
  • © 2000

Overview

Editors:
  1. Alvaro Macieira-Coelho

    1. University of Paris VI, Versailles, France

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  • This book focusses on an area of increasing interest:
  • the role of the cell matrix in cell regulation
  • Includes supplementary material: sn.pub/extras

Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 25)

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Table of contents (7 chapters)

  1. Front Matter

    Pages I-X
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  2. Topological Constraints Carry Signaling from the Cell Matrix to the Genome

    • Alvaro Macieira-Coelho
    Pages 1-19

  3. The Transmission of Contractility Through Cell Adhesion

    • Kyoko Imanaka-Yoshida
    Pages 21-35

  4. Role of Focal Adhesion Kinase in Signaling by the Extracellular Matrix

    • Ji-He Zhao, Jun-Lin Guan
    Pages 37-55

  5. Interaction Between Cells and Extracellular Matrix: Signaling by Integrins and the Elastin-Laminin Receptor

    • J. Labat-Robert, L. Robert
    Pages 57-70

  6. Regulation of Gene Expression by Changes in Cell Adhesion

    • Takejiro Kuzumaki
    Pages 71-87

  7. Expression of Liver Specific-Genes in Hepatocytes Cultured in Collagen Gel Matrix

    • Maria José Gómez-Lechón, Ramiro Jover, Teresa Donato, Xavier Ponsoda, José V. Castell
    Pages 89-104

  8. Collagen Type I: A Substrate and a Signal for Invasion

    • Leen Van Hoorde, Elisabeth Van Aken, Marc Mareel
    Pages 105-134

  9. Back Matter

    Pages 135-136
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Keywords

About this book

This book covers a hot subject in cell biology; i.e. how the cell environment sends messages to the cell, regulates gene expression, and modulates the cell phenotype. For a long time the extracellular matrix was believed to have only a supporting role for cell attachement. However, it became apparent that the matrix participates actively in cell metabolism. The experiments that led to this conclusion are described in this volume. Progressively, molecules have been identified that transmit this signaling at the cell-matrix interface. Their identity and mechanism of action are also illustrated in this book. Finally, it explains the role the cell-matrix relationship plays in the regulation of cell proliferation, cell differentiation, and the expression of malignancy.

Editors and Affiliations

  • University of Paris VI, Versailles, France

    Alvaro Macieira-Coelho

Bibliographic Information

  • Book Title: Signaling Through the Cell Matrix

  • Editors: Alvaro Macieira-Coelho

  • Series Title: Progress in Molecular and Subcellular Biology

  • DOI: https://doi.org/10.1007/978-3-642-59766-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2000

  • Softcover ISBN: 978-3-642-64117-6Published: 27 September 2011

  • eBook ISBN: 978-3-642-59766-4Published: 06 December 2012

  • Series ISSN: 0079-6484

  • Series E-ISSN: 2197-8484

  • Edition Number: 1

  • Number of Pages: X, 136

  • Topics: Cell Biology, Cancer Research

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