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  • Book
  • © 2011

Glycans in Diseases and Therapeutics

  • Provides timely reviews on current topics of ECM biology.-
  • Improves our understanding of the cellbiological background of diseases.-
  • Published in collaboration with the American Society for Matrix Biology.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biology of Extracellular Matrix (BEM)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xi
  2. Heparan Sulfate Proteoglycans in Infection

    • Allison H. Bartlett, Pyong Woo Park
    Pages 31-62
  3. Glycans in Cancer

    • Lubor Borsig
    Pages 63-81
  4. Glycosaminoglycans in Atherosclerosis and Thrombosis

    • C. P. Vicente, J. A. P. Godoy, C. C. Werneck
    Pages 83-111
  5. Glycans in Embryonic Stem Cells

    • Claire Pickford, Rebecca Holley, Kate Meade, Catherine Merry
    Pages 113-137
  6. Heparan Sulfate Proteoglycans in Cancer Therapy

    • Ezeddin Salem Gassar, Sherif A. Ibrahim, Martin Götte
    Pages 139-158
  7. Structure and Biological Activities of Glycosaminoglycan Analogs from Marine Invertebrates: New Therapeutic Agents?

    • Eliene O. Kozlowski, Angélica M. Gomes, Christiane Sobral Silva, Mariana Sá Pereira, Ana Cristina E. S. de Vilela Silva, Mauro S. G. Pavão
    Pages 159-184
  8. Back Matter

    Pages 185-188

About this book

Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.

This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.

Editors and Affiliations

  • , Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Mauro S.G. Pavão

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access