Overview
- Provides timely reviews on current topics of ECM biology
- Improves our understanding of the role of matrix-degrading proteases in tissue remodeling and diseases
- The series is published in collaboration with the American Society for Matrix Biology
- Includes supplementary material: sn.pub/extras
Part of the book series: Biology of Extracellular Matrix (BEM)
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.
Editors and Affiliations
Bibliographic Information
Book Title: Extracellular Matrix Degradation
Editors: William C. Parks, Robert P. Mecham
Series Title: Biology of Extracellular Matrix
DOI: https://doi.org/10.1007/978-3-642-16861-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2011
Hardcover ISBN: 978-3-642-16860-4Published: 09 April 2011
Softcover ISBN: 978-3-642-26780-2Published: 29 May 2013
eBook ISBN: 978-3-642-16861-1Published: 07 April 2011
Series ISSN: 0887-3224
Series E-ISSN: 2191-1959
Edition Number: 1
Number of Pages: X, 255
Topics: Cell Biology, Biochemistry, general, Protein Science, Molecular Medicine