Editors:
- First volume of this re-launched series -
- An excellent introduction to the biology of the extracellular matrix -
- Published in collaboration with the American Society for Matrix Biology
- Includes supplementary material: sn.pub/extras
Part of the book series: Biology of Extracellular Matrix (BEM)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (11 chapters)
-
Front Matter
-
Back Matter
About this book
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling.
This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Editors and Affiliations
-
School of Medicine, Dept. Cell Biology & Physiology, Washington University, St. Louis, USA
Robert P. Mecham
Bibliographic Information
Book Title: The Extracellular Matrix: an Overview
Editors: Robert P. Mecham
Series Title: Biology of Extracellular Matrix
DOI: https://doi.org/10.1007/978-3-642-16555-9
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2011
Hardcover ISBN: 978-3-642-16554-2Published: 17 February 2011
Softcover ISBN: 978-3-642-26719-2Published: 21 April 2013
eBook ISBN: 978-3-642-16555-9Published: 16 February 2011
Series ISSN: 0887-3224
Series E-ISSN: 2191-1959
Edition Number: 1
Number of Pages: XIV, 426
Topics: Cell Biology, Protein Science, Molecular Medicine