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Life Sciences - Cell Biology | Innate Immunity of Plants, Animals and Humans

Innate Immunity of Plants, Animals and Humans

Heine, Holger (Ed.)

2008, XIV, 241 p.

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  • Gives a state-of-the-art overview of innate immunity across the evolutionary tree
  • Covers very ancient and diverse species as well as extensive reviews of drosophila and mammalian innate immune mechanisms
  • Provides a broad understanding of the current knowledge in this field

All living organisms are in a constant battle against their environment. Since uncontained microorganisms would simply overgrow all higher animals, the evolution of multicellular organisms required adequate and efficient defense mechanisms to protect their own integrity and to ensure their own survival. These defense mechanisms, encompassing receptor proteins that sense the presence of pathogens and effector molecules that are involved in controlling them, are the elemental parts of the innate immune system.

For many species, the innate immune system is the sole active defense system. Long thought to be an unspecific immune response, the discovery of the Toll-like receptors and their ligands finally revealed just how specific the innate immune response actually is.

This book wants to give an overview of our current knowledge about the innate immune system of plants, animals and humans. It not only covers the innate immune mechanisms and responses of so diverse organisms such as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans as well as the central defense mechanisms, antimicrobial peptides and the complement system.

Content Level » Research

Keywords » Danio rerio - Defense Mechanisms - Drosophila - Immune System - Immunity - Innate Immunity - Vertebrate - defense mechanism - evolution - microorganisms - proteins

Related subjects » Biochemistry & Biophysics - Cell Biology - Evolutionary & Developmental Biology - Immunology

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