Overview
- Together with the preceding volume in the series, this book covers all major aspects of meiotic research
- The chapters are written by expert researchers who significantly contributed to the progress in their fields
Part of the book series: Genome Dynamics and Stability (GENOME, volume 3)
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm – in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.
Bibliographic Information
Book Title: Recombination and Meiosis
Book Subtitle: Models, Means, and Evolution
Editors: Richard Egel, Dirk-Henner Lankenau
Series Title: Genome Dynamics and Stability
DOI: https://doi.org/10.1007/978-3-540-68984-3
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-68983-6Published: 18 August 2008
Softcover ISBN: 978-3-642-08850-6Published: 25 November 2010
eBook ISBN: 978-3-540-68984-3Published: 25 July 2008
Series ISSN: 1861-3373
Series E-ISSN: 1861-3381
Edition Number: 1
Number of Pages: XXI, 390
Topics: Cell Biology, Biochemistry, general, Animal Genetics and Genomics, Human Genetics, Plant Genetics and Genomics