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Stem Cells & Regenerative Medicine

From Molecular Embryology to Tissue Engineering

  • Book
  • © 2011

Overview

Editors:
  1. Krishnarao Appasani

    1. Gene Expression Systems, Inc., Waltham, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Raghu K. Appasani

    1. Student Science, Middletown, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Offers a comprehensive review of the subject matter
  • Chapters are written by leading scientists and researchers in the field
  • Foreword written by renowned scholar, Professor John Gurdon
  • Includes supplementary material: sn.pub/extras

Part of the book series: Stem Cell Biology and Regenerative Medicine (STEMCELL)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xxvii
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  2. Stem Cell Biology

    1. Front Matter

      Pages 1-1
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    2. Introduction to Stem Cells and Regenerative Medicine

      • Krishnarao Appasani, Raghu K. Appasani
      Pages 3-18

    3. Embryonic Stem Cells: Discovery, Development, and Current Trends

      • Elias Theodorou, Michael Snyder
      Pages 19-43

    4. Bmi1 in Self-Renewal and Homeostasis of Pancreas

      • Eugenio Sangiorgi, Mario Capecchi
      Pages 45-57

    5. Cancer Stem Cells in Solid Tumors

      • Elodie du Potet, Lauren Cameron, Nagy A. Habib, Natasa Levicar
      Pages 59-76

    6. Adipose-Derived Stem Cells and Skeletal Muscle Repair

      • Claude A. Dechesne, Didier F. Pisani, Sébastien Goudenege, Christian Dani
      Pages 77-87

    7. Regeneration of Sensory Cells of Adult Mammalian Inner Ear

      • Dongguang Wei, Ebenezer N. Yamoah
      Pages 89-101

    8. Stem Cells and Their Use in Skeletal Tissue Repair

      • Laura Baumgartner, Vuk Savkovic, Susanne Trettner, Colette Martin, Nicole I. zur Nieden
      Pages 103-124

  3. Epigenetic and microRNA Regulation in Stem Cells

    1. Front Matter

      Pages 125-125
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    2. Epigenetic Identity in Cancer Stem Cells

      • Maria Ouzounova, Hector Hernandez-Vargas, Zdenko Herceg
      Pages 127-139

    3. Function of MicroRNA-145 in Human Embryonic Stem Cell Pluripotency

      • Na Xu, Kenneth S. Kosik
      Pages 141-153

    4. Mesenchymal Stem Cells for Liver Regeneration

      • Tom K. Kuo, Yueh-Hsin Ping, Oscar K. Lee
      Pages 155-179

  4. Stem Cells for Therapeutic Applications

    1. Front Matter

      Pages 193-193
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    2. The Role of Time-Lapse Microscopy in Stem Cell Research and Therapy

      • Kevin E. Loewke, Renee A. Reijo Pera
      Pages 181-191

    3. Therapeutic Applications of Mesenchymal Stem/Multipotent Stromal Cells

      • Weian Zhao, Debanjan Sarkar, James Ankrum, Sean Hall, Weili Loh, Wei Suong Teo et al.
      Pages 195-218

    4. Gastrointestinal Stem Cells

      • N. Parveen, Aleem A. Khan, M. Aejaz Habeeb, C. M. Habibullah
      Pages 219-225

    5. Lung Epithelial Stem Cells

      • Magnus Karl Magnusson, Olafur Baldursson, Thorarinn Gudjonsson
      Pages 227-241

    6. Placental-Derived Stem Cells: Potential Clinical Applications

      • Sean Murphy, Euan Wallace, Graham Jenkin
      Pages 243-263

    7. Bone Marrow Cell Therapy for Acute Myocardial Infarction: A Clinical Trial Review

      • Franca S. Angeli, Yerem Yeghiazarians
      Pages 265-277
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Keywords

About this book

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Reviews

From the reviews:

“The Introduction by the two editors is clearly telling the aim of such a bible, to cover from the basic aspects of molecular embriology dealing with the stemness cellular capacity … till the new challenging opportunities of tissue engineering. I think the price of the book (€ 170) is worthy enough for what the reader will get. … a book with all the figures in colour, this is a great help while looking at cytology, histology or entangled graphs!” (Carlo Alberto Redi, European Journal of Histochemistry, Vol. 55, 2011)

Editors and Affiliations

  • Gene Expression Systems, Inc., Waltham, USA

    Krishnarao Appasani

  • Student Science, Middletown, USA

    Raghu K. Appasani

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