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Vaccine Protocols

  • Book
  • © 1996

Overview

Editors:
  1. Andrew Robinson

    1. Centre for Applied Microbiology and Research, Porton Down, UK

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  2. Graham H. Farrar

    1. Centre for Applied Microbiology and Research, Porton Down, UK

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    You can also search for this editor in PubMed   Google Scholar

  3. Christopher N. Wiblin

    1. Centre for Applied Microbiology and Research, Porton Down, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 4)

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Table of contents (22 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Overview of Vaccines

    • Gordon Ada
    Pages 1-16

  3. Temperature-Sensitive Mutant Vaccines

    • Craig R. Pringle
    Pages 17-32

  4. Live Viral Vectors

    • Alan Warnes, Anthony R. Fooks
    Pages 33-45

  5. Development of Attenuated Salmonella Strains that Express Heterologous Antigens

    • Richard J. Anderson, L. Patricia Londoño, Derek J. Pickard, Gordon Dougan
    Pages 47-62

  6. Chimeric Proteins

    • Riny Janssen, Jan Tommassen
    Pages 63-74

  7. Synthetic Peptides

    • Michael J. Francis
    Pages 75-90

  8. Genetic Detoxification of Bacterial Toxins

    • Mariagrazia Pizza, Maria Rita Fontana, Vincenzo Scarlato, Rino Rappuoli
    Pages 91-109

  9. Polysaccharicb-Conjugate Vaccines

    • Carla C. A. M. Peeters, Patrick R. Lagerman, Odo de Weers, Lukas A. Oomen, Peter Hoogerhout, Michel Beurret et al.
    Pages 111-133

  10. The Use of Adjuvants in Experimental Vaccines

    • Duncan E. S. Stewart-Tull
    Pages 135-139

  11. The Use of Adjuvants in Experimental Vaccines

    • Duncan E. S. Stewart-Tull
    Pages 141-145

  12. The Use of Adjuvants in Experimental Vaccines

    • Duncan E. S. Stewart-Tull
    Pages 147-151

  13. The Use of Adjuvants in Experimental Vaccines

    • Duncan E. S. Stewart-Tull
    Pages 153-155

  14. Microencapsulation of Vaccines

    • David H. Jones
    Pages 157-166

  15. Lyophilization of Vaccines

    • Gerald D. J. Adams
    Pages 167-185

  16. Stimulation of Mucosal Immunity

    • David J. M. Lewis, Christopher M. M. Hayward
    Pages 187-195

  17. Induction and Detection of T-Cell Responses

    • Kingston H. G. Mills
    Pages 197-221

  18. Immunological Characterization

    • Keith Redhead
    Pages 223-229

  19. Severe Combined lmmunodeficient (SCID) Mice in Vaccine Assessment

    • Brian W. McBride
    Pages 231-249

  20. Clinical Trials

    • Paddy Farrington, Elizabeth Miller
    Pages 251-268
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About this book

The production of a book devoted to Vaccine Protocols has proved to be a complex task; the variety of procedures required to design, develop, pro­ duce, and assess a vaccine is immense and covers aspects of chemistry, bio­ chemistry, molecular biology, and immunology. Many of the previous volumes in the Methods in Molecular Biology series provide the background required for work on vaccines; of particular interest are the volumes on Immunochemi­ cal Protocols, Practical Molecular Virology, Proteins, and Nucleic Acids. In the volume on Vaccine Protocols, we have tried to cover the latest scientific methods for the design, production, and assessment of vaccines against viruses, bacteria, and parasites. Essentially, the volume is comprised of three basic chapter types. First, a number of chapters describe in detail the development and production of vac­ cines by specific techniques, including genetic manipulation of viruses or bac­ teria to produce live attenuated vaccines or inactivated toxins, and the production of synthetic peptides and conjugate vaccines. Second, a similar number of chapters describe more general techniques that can be used for the formulation, delivery, and assessment of immune responses to vaccines.

Reviews

"...a valuable basic reference manual of vaccine related laboratory procedures...strongest in the area of vaccine development and delivery technology...especially valuable to those new to the field of vaccine development and formulation." -Doody's Health Sciences Book Review Journal

" ...this book should prove to be a valuable aid to all those seeking to produce improved or novel vaccines." -Unlisted Drugs

"...serves as a valuable source of information on nonviral and viral gene delivery..." - Pharmaceutical Research

"...useful and will serve many in the vaccine reseach and development community quite well...provides practical advice, a commodity that is ofen difficult to find in printed and scientific and manufacturing literature." - Clinical Infectious Diseases

Editors and Affiliations

  • Centre for Applied Microbiology and Research, Porton Down, UK

    Andrew Robinson, Graham H. Farrar, Christopher N. Wiblin

Bibliographic Information

  • Book Title: Vaccine Protocols

  • Editors: Andrew Robinson, Graham H. Farrar, Christopher N. Wiblin

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/0896033341

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 1996

  • eBook ISBN: 978-1-59259-588-4Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: X, 317

  • Topics: Cell Biology

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