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  • Book
  • © 2001

Physiology of Inflammation

Editors:

  • Covers the physiological process relevant to inflammation
  • Addressed from a vascular perspective
  • Intended to serve as an advanced textbook or reference for those studying the physiology of inflammation

Part of the book series: Methods in Physiology (METHPHYS)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xiii
  2. History of Inflammation Research

    • Klaus Ley
    Pages 1-10
  3. Formation and Differentiation of Leukocytes

    • Douglas E. Wright, Irving L. Weissman
    Pages 11-51
  4. Blood Flow Regulation in Inflammation

    • Joel Linden
    Pages 52-64
  5. Microvascular Permeability in Inflammation

    • Virginia H. Huxley, Rolando E. Rumbaut
    Pages 65-79
  6. Cytokines and Endothelial Cell Activation

    • Francis W. Luscinskas
    Pages 80-89
  7. Chemokines and Chemokine Receptors

    • Andrew D. Luster, James MacLean
    Pages 90-110
  8. Lipid Mediators of Inflammation

    • Per Hedqvist, Lennart Lindbom
    Pages 111-130
  9. Complement in Inflammation

    • B. Paul Morgan
    Pages 131-145
  10. Chemoattractant Receptor-G-Protein Coupling

    • Katharina Wenzel-Seifert, Roland Seifert
    Pages 146-188
  11. Antimicrobial Activity of Leukocytes

    • Bernard M. Babior, Carolyn R. Hoyal, Robert I. Lehrer, Tomas Ganz
    Pages 189-203
  12. In Vitro Flow Models of Leukocyte Adhesion

    • Michael B. Lawrence
    Pages 204-221
  13. Selectins and Their Ligands in Inflammation

    • Geoffrey S. Kansas
    Pages 222-241
  14. β2 Integrins and Their Ligands in Inflammation

    • Michael L. Dustin
    Pages 242-262
  15. VCAM-1 and Its Ligands

    • Sharon J. Hyduk, Myron I. Cybulsky
    Pages 263-284
  16. Soluble Leukocyte-Endothelial Adhesion Molecules

    • Christopher D. Buckley, David H. Adams, David L. Simmons
    Pages 285-302
  17. Transmigration of Leukocytes

    • Brian Stein, Yeesim Khew-Goodall, Mathew Vadas
    Pages 338-380
  18. Knockout Mice in Inflammation Research

    • Daniel C. Bullard
    Pages 381-401
  19. Interface Between Inflammation and Coagulation

    • Dario C. Altieri
    Pages 402-422

About this book

This book covers the physiological processes relevant to inflammation. Although the problem is addressed from a vascular perspective, pathological aspects are also considered. The book centers on the recruitment of leukocytes to sites of injury and infection, their function in the tissue, and the eventual resolution of inflammation. It starts with the formation of leukocytes and the physiology of their transport to the sites of inflammation, considers endothelial activation, and covers all kinds of leukocyte activators including chemokines. Signal transduction pathways for chemoattractants and the activation of neutrophil functions are discussed. Several chapters review the various adhesion molecules and pertinent methods to study their function, including flow chambers, knockout mice, measurement of soluble adhesion molecules and intravital microscopy. The book is aimed at medical residents, graduate students, postdoctoral fellows, and physicians and scientists in physiology, pharmacology, biomedical engineering, pathology, immunology, infectious disease and related disciplines. It is intended to serve as an advanced textbook or reference for studying the physiology of inflammation.

Editors and Affiliations

  • Department of Biomedical Engineering, University of Virginia School of Medicine, Charlottesville, USA

    Klaus Ley

Bibliographic Information

  • Book Title: Physiology of Inflammation

  • Editors: Klaus Ley

  • Series Title: Methods in Physiology

  • DOI: https://doi.org/10.1007/978-1-4614-7512-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: American Physiological Society 2001

  • eBook ISBN: 978-1-4614-7512-5Published: 27 May 2013

  • Series ISSN: 2628-7471

  • Series E-ISSN: 2628-748X

  • Edition Number: 1

  • Number of Pages: 546

  • Additional Information: Originally Published by Oxford University Press 2001

  • Topics: Cell Physiology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access