Skip to main content
  • Book
  • © 2005

Rho Family GTPases

Part of the book series: Proteins and Cell Regulation (PROR, volume 3)

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiii
  2. The Rho GTPases

    • Ed Manser
    Pages 1-18
  3. Evolution of the Human Rho GTPase Family

    • Stephanie Pellegrin, Harry Mellor
    Pages 19-29
  4. Structural Analysis of Rho Protein Complexes

    • Darerca Owen, Helen R. Mott
    Pages 31-72
  5. Activation of GTPases by Dock180 Family of Proteins

    • Mingjian Lu, Kodi S. Ravichandran
    Pages 73-92
  6. Rho GAPs — Regulators of Rho GTPases and More

    • Tom Jacobs, Christine Hall
    Pages 93-112
  7. RhoA/C and the Actin Cytoskeleton

    • Yoji Kawano, Takako Kaneko-Kawano, Takeshi Yoshimura, Saeko Kawabata, Kozo Kaibuchi
    Pages 113-136
  8. Cdc42 and Rac Control of the Actin Cytoskeleton

    • Cheng-Gee Koh, Louis Lim
    Pages 137-156
  9. Regulation of Cell-Cell Adhesion by Rho Family GTPases

    • Astrid Kraemer, Alpha S. Yap
    Pages 157-189
  10. Rho Proteins and Vesicle Trafficking

    • Ivan De Curtis
    Pages 191-210
  11. The Prototype Rho-Associated Kinase PAK

    • Zhuo-Shen Zhao
    Pages 211-230
  12. Genetic Analysis of Rho Protein Function in Mice

    • Raffaella Sordella, Jeffrey Settleman
    Pages 231-263
  13. Rho Proteins and Microtubules

    • Christina H. Eng, Gregg G. Gundersen
    Pages 265-296
  14. Back Matter

    Pages 297-297

About this book

Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted.

The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases.

The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.

Editors and Affiliations

  • Institute of Molecular and Cell Biology, Singapore

    Ed. Manser

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access