Regenerative Medicine and Cell Therapy

1. Front Matter

   Pages i-xiv

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2. Cell Therapy for Neurodegenerative Disorders

   • Ilyas Singec

   Pages 1-22

3. New Prospects for Neural Stem Cell Therapies of Nervous System Diseases Toward the Establishment of Atypical Ectopic Perivascular Stem Cell Niches

   • Clara Alfaro-Cervello, Chiara Cossetti, Elena Giusto, Matteo Donegà, Stefano Pluchino

   Pages 23-39

4. Cultured Limbal Epithelial Stem Cell Therapy for Ocular Surface Diseases

   • Hannah J. Levis, Julie T. Daniels, Sajjad Ahmad

   Pages 41-56

5. Keratinocyte Stem Cells: Biology and Clinical Applications

   • Carlo Pincelli, Alessandra Marconi

   Pages 57-64

6. Cardiac Regeneration with Stem Cells

   • Beatriz Pelacho, Manuel Mazo, Sheyla Montori, Ana Maria Simon-Yarza, Juan Jose Gavira, Maria J. Blanco-Prieto et al.

   Pages 65-112

7. Development of Biological Approaches to Improve Muscle Healing After Injury and Disease

   • Jonathan D. Proto, Johnny Huard

   Pages 113-130

8. Mesenchymal Stem Cells in Bone and Cartilage Regeneration

   • Mohamadreza Baghaban Eslaminejad, Elham Zomorodian, Fatemeh Bagheri

   Pages 131-153

9. Pancreatic Reprogramming

   • Juan Domínguez-Bendala

   Pages 155-168

10. Pancreatic Regeneration in the Face of Diabetes

    • Zeeshan Ahmad

    Pages 169-201

11. Regenerative Therapies for Liver Diseases

    • Amar Deep Sharma, Ina Rittelmeyer, Tobias Cantz, Michael Ott

    Pages 203-231

12. Clinical Studies of Cell Therapy for Liver Cirrhosis

    • James A. Thomas, Stuart J. Forbes

    Pages 233-243

13. Stem Cell Applications for the Treatment of Gastrointestinal System Diseases

    • Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz, Damián García-Olmo

    Pages 245-277

14. Germ Line Stem Cells: A Promising Alternative Source for Stem-Cell-Based Therapies in Regenerative Medicine

    • Ellen Goossens, Herman Tournaye

    Pages 279-300

15. Cord Blood Stem Cells and Regenerative Medicine

    • David T. Harris

    Pages 301-312

16. Back Matter

    Pages 313-316

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Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

• Aghdami
• Application
• Baharvand
• Cell therapy
• Medicine
• Regenerative
• Therapeutic

• Royan Institute, Department of Developmental Biology, University of Science and Culture, Tehran, Iran

  Hossein Baharvand

• , Regenerative Medicine, Royan Institute for Stem Cell Biology an, Tehran, Iran

  Nasser Aghdami

Hossein Baharvand, PhD

Born in 1972, Hossein Baharvand received his Ph.D degree from University for Teacher Training (TARBIAT MOALEM), Tehran in 2004 in the field of Developmental Biology. He joined Royan institute when he was M.Sc. student in 1995.  He is currently professor and director of Royan Institute for Stem Cell Biology and Technology (2002-now) and head of Department of Developmental Biology at University of Science and Culture (2006-now). He established the first mouse and human embryonic stem cells in Iran (2003). Later his team has generated several mouse and human embryonic and induced pluripotent stem cells (2008). This has enabled them to pursue many avenues of research into translational research and regenerative medicine. He has published 130 international and 98 national peer-reviewed papers, as well as five chapters in international books, six books in Persian, and translated six English text books into Persian. He was editor of three international books (2009, 2012, Humana press, Springer, USA). He is editorial board member of eight international journals and was as invited speaker in several meetings. He has received 18 international and national prizes including 10^th (2004), 12^th (2006), and 17^th (2012) annual Razi research festival on medical sciences, 27^th annual book of the year of the Islamic republic of Iran (2010), Academy of Medical Sciences of Iran (Dr. Hadavi’s Award, 2010), Sicence and Technology Prize of the Islamic Educational, Scientific, and Cultural Organization (ISESCO) in the field of Biology (2010).    

 

 

Nasser Aghdami,  MD, PhD
Born in 1971 in Iran, Nasser Aghdami received his MD degree from Urumieh Medical University in 1998 and PhD in Immunology in 2007 from Tarbiat Modares University, Iran. He joined the Hematology, Oncology and BMT Research Center in 2000 as a principal investigator and Royan Institutefor Stem Cell Biology and Technology in 2006. Dr. Aghdami’s research has focused on the development of cardiovascular development, translational research, and the role of stem cells in tissue regeneration.   Since 2008, he is the Head of the Department of Regenerative Medicine and Royan Cell Therapy Center. In this regard, clinical trial design and performance is one of his responsibilities. He has served on numerous national grant review committees, advisory panels and editorial boards related to stem cells, clinical trials, and cell therapy. Dr. Aghdami has published 21 international and 10 national peer-reviewed papers, as well as three chapters in international books, two books in Farsi, and translated one book into Farsi.

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