Logo - springer
Slogan - springer

Life Sciences | Calcium Handling in hiPSC-Derived Cardiomyocytes

Calcium Handling in hiPSC-Derived Cardiomyocytes

Yee-Ki, Lee, Chung-Wah, Siu

2012, XII, 52 p. 18 illus., 17 illus. in color.

Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-1-4614-4093-2

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase

learn more about Springer eBooks

add to marked items


Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-1-4614-4092-5

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days

add to marked items

  • With numerous color figures

Content Level » Research

Keywords » Calcium - Cardiac regeneration - cardiomyopathy - hiPSC

Related subjects » Cardiology & Angiology - Cell Biology - Life Sciences

Table of contents 

Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.

Table of contents:

Myocardial Infarction and Heart Failure.- Embryonic Stem Cells/ Pluripotent Stem Cells.- Human Induced Pluripotent Stem Cell (hiPSC)-derived Cardiomyocytes as a Source for Cardiac Regeneration.- Calcium Homeostasis in Cardiomyocytes.- Sarcoplasmic Reticulum (SR) Governs Maturity of Cardiomyocytes.- SR Junctional Proteins Play a Role in Calcium Flux Between Cytosol and SR.- Spatial and Temporal Ca2+ Wavefront Dictated by T-tubule Structure.- IP3-Mediated Calcium Release Contributes to Whole-Cell Calcium Transients.- Calcium Handling Properties of hES-derived Cardiomyocytes.- iPSC-derived Cardiomyocyte as A Potential Platform for Disease Modellig of Impaired Calcium-Handling Related Syndrome.- Measurement of Cytosolic [Ca2+] by Fluorescence Confocal Microscopy.- Excitation-Contraction (EC) Coupling Assessment.- Limitation and Future Studies.

Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Stem Cells.