Logo - springer
Slogan - springer

Life Sciences | NanoCellBiology of Secretion - Imaging Its Cellular and Molecular Underpinnings

NanoCellBiology of Secretion

Imaging Its Cellular and Molecular Underpinnings

Jena, Bhanu P.

2012, XII, 70p. 38 illus., 33 illus. in color.

Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-1-4614-2438-3

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase

learn more about Springer eBooks

add to marked items


Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-1-4614-2437-6

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days

add to marked items

  • About this book


Content Level » Professional/practitioner

Keywords » biological imaging - cell secretion - nanotechnology - spectroscopy

Related subjects » Cell Biology - Condensed Matter Physics - Life Sciences

Table of contents 

Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists.

Table of contetns:

Introduction.- Materials & Methods.- Porosome Discovery.-  Calcium & SNARE-Induced Membrane Fusion.- SNAREs need to reside in opposing membrane.- Membrane curvature dictates SNARE size.- Disassembly of membrane-associated SNARE complex.- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly.- SNAREs bring opposing bilayers closer for calcium bridging.- Membrane lipids influence SNARE complex assembly-disassembly.- Vesicle swelling and content expulsion during cell secretion.- Secretory vesicle swelling is required for intravesicular content expulsion.- Molecular mechanism of secretory vesicle swelling.- Presence of beta receptors at the secretory vesicle membrane.- Conclusion and future studies.​

Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Biological Microscopy.