Logo - springer
Slogan - springer

Life Sciences | Bioconductor Case Studies

Bioconductor Case Studies

Series: Use R!

Hahne, F., Huber, W., Gentleman, R., Falcon, S.


Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-0-387-77240-0

digitally watermarked, no DRM

Included Format: PDF

download immediately after purchase

learn more about Springer eBooks

add to marked items


Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-0-387-77239-4

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days

add to marked items

  • Dynamic document: all computations and figures can be reproduced on a local computer
  • Real data case studies and hands on exercises
  • Companion website offering color figures and solutions to exercises

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include

* import and preprocessing of data from various sources

* statistical modeling of differential gene expression

* biological metadata

* application of graphs and graph rendering

* machine learning for clustering and classification problems

* gene set enrichment analysis

Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

The authors of this book have longtime experience in teaching introductory and advanced courses to the application of Bioconductor software. Florian Hahne is a Postdoc at the Fred Hutchinson Cancer Research Center in Seattle, developing novel methodologies for the analysis of high-throughput cell-biological data. Wolfgang Huber is a research group leader in the European Molecular Biology Laboratory at the European Bioinformatics Institute in Cambridge. He has wide-ranging experience in the development of methods for the analysis of functional genomics experiments. Robert Gentleman is Head of the Program in Computational Biology at the Fred Hutchinson Cancer Research Center in Seattle, and he is one of the two authors of the original R system. Seth Falcon is a member of the R core team and former project manager and developer for the Bioconductor project.

Content Level » Research

Keywords » Annotation - Bioinformatics - Clustering - Computational biology - Computer - Machine learning - Microarray - Networks - biology - calculus - classification - genome - modeling

Related subjects » Bioinformatics - Life Sciences - Life Sciences, Medicine & Health - Systems Biology and Bioinformatics

Table of contents / Preface / Sample pages 

Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Life Sciences (general).