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Structure, Dynamics and Function of Biomolecules

The First EBSA Workshop A Marcus Wallenberg Symposium

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. Anders Ehrenberg

    1. Department of Biophysics Arrhenius Laboratory, University of Stockholm, Stockholm, Sweden

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  2. Rudolf Rigler

    1. Department of Medical Biophysics, Karolinska Institutet, Stockholm, Sweden

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  3. Astrid Gräslund

    1. Department of Biophysics Arrhenius Laboratory, University of Stockholm, Stockholm, Sweden

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  4. Lennart Nilsson

    1. Department of Medical Biophysics, Karolinska Institutet, Stockholm, Sweden

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Part of the book series: Springer Series in Biophysics (BIOPHYSICS, volume 1)

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Table of contents (63 papers)

  1. Front Matter

    Pages I-XVI
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  2. Introductory Keynotes

    1. The Nature of Mechanical Devices in Biological Systems

      • Robert J. P. Williams
      Pages 1-4

    2. Physical Chemistry and Biological Strategy of Antigen Recognition

      • Harden M. McConnell
      Pages 5-9

  3. Structure and Dynamics of Heme Proteins

    1. Heme Protein Reactions: Models, Concepts, and Problems

      • Hans Frauenfelder
      Pages 10-14

    2. Multiple Conformational States of Myoglobin: A Molecular Dynamics Analysis

      • R. Elber, M. Karplus
      Pages 15-19

    3. Dynamics of Structural Changes in Hemoglobin

      • Eric R. Henry, James Hofrichter, William A. Eaton
      Pages 20-24

    4. Structure and Dynamics of Photodissociated Myoglobin

      • Denis L. Rousseau, Massimo Sassaroli, Siddharth Dasgupta
      Pages 25-29

    5. Structural Fluctuations in Myoglobin

      • F. Parak, H. Hartmann, G. U. Nienhaus, J. Heidemeier
      Pages 30-33

    6. Glass Transition of Hydration Water and Structural Flexibility of Myoglobin

      • Wolfgang Doster
      Pages 34-38

    7. Pressure Studies of Large-Scale Protein Motions

      • Robert D. Young
      Pages 39-42

    8. Viscosity and Glycerol Effects on Dynamics of Cytochrome c

      • Anders Ehrenberg
      Pages 43-46

    9. Kinetics of Geminate Recombination Following Photodissociation of Mutant (Carbonmonoxy)Hemoglobins

      • Marie-Pierre Fontaine, Lars Lindqvist
      Pages 47-50

  4. Physical Aspects of Biomolecular Dynamics and Kinetics

    1. Thermodynamics of Enzyme Folding and Activity: Theory and Experiment

      • Chung F. Wong, J. Andrew McCammon
      Pages 51-55

    2. Progress and Problems in the Study of Protein Dynamics by X-Ray Diffraction

      • Gregory A. Petsko
      Pages 56-60

    3. Activation Free Energies of Enzymatic Reactions; Simulations and Experiments

      • Arieh Warshel
      Pages 61-64

    4. Simple Models for the Dynamics of Biomolecules: How Far Can We Go?

      • William Bialek, Robert F. Goldstein, Steven Kivelson
      Pages 65-69

    5. Condensed Matter Biophysics: Structure and Dynamics of Large Biomolecules

      • D. L. Stein
      Pages 70-74

    6. Molecular Dynamics Simulation of Parvalbumin in Aqueous Solution

      • Peter Ahlström, Olle Teleman, Bo Jönsson, Sture Forsén
      Pages 75-81

    7. Cooperative Ion Binding to Proteins. A Statistical Mechanical Approach

      • Peter Ahlström, Bo Jönsson, Clifford Woodward, Olle Teleman
      Pages 82-85

    8. Single Step Kinetics of Enzyme Dynamics

      • Pierre Douzou, Gaston Hui Bon Hoa
      Pages 86-92
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Keywords

About this book

This is a collection of papers presented and discussed at the first EBSA workshop held at Saltsj6baden outside stockholm in Sweden, July 6-10, 1986. The common theme of these papers is dynamics of biomolecules, and how the dynamics depends on the molecular structure and organi­ zation, and connects to and determines the biological function. This is a rapidly expanding field of research which combines many different aspects of molecular bio­ physics. Much material is new and presented for the first time. Even if the work so far has been of the kind that is usually called basic research, practical applications are clearly indicated in some articles, and are waiting around the corner in several other cases. At the workshop only one third of the time was used for the formal presentations and two thirds for discussion. To this should also be added discussions during the poster sessions. During these lively and unrecorded discussions fresh viewpoints emerged and new ideas were created. Ad­ mittedly, our knowledge at present is only fragmentary but when pieces of the puzzle are brought together at a workshop or in a publication of this kind more extended and sometimes unexpected contours and shapes become vi­ sible. It is our hope that this rapid publication of camera-ready manuscripts will transfer some of the spi­ rit at the workshop to the reader, and in his or her institute or laboratory initiate further discussions, bring forward more ideas and start new experimental ap­ roaches.

Editors and Affiliations

  • Department of Biophysics Arrhenius Laboratory, University of Stockholm, Stockholm, Sweden

    Anders Ehrenberg, Astrid Gräslund

  • Department of Medical Biophysics, Karolinska Institutet, Stockholm, Sweden

    Rudolf Rigler, Lennart Nilsson

Bibliographic Information

  • Book Title: Structure, Dynamics and Function of Biomolecules

  • Book Subtitle: The First EBSA Workshop A Marcus Wallenberg Symposium

  • Editors: Anders Ehrenberg, Rudolf Rigler, Astrid Gräslund, Lennart Nilsson

  • Series Title: Springer Series in Biophysics

  • DOI: https://doi.org/10.1007/978-3-642-71705-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1987

  • Softcover ISBN: 978-3-642-71707-9Published: 17 November 2011

  • eBook ISBN: 978-3-642-71705-5Published: 06 December 2012

  • Series ISSN: 0932-2353

  • Series E-ISSN: 1868-2561

  • Edition Number: 1

  • Number of Pages: XVI, 304

  • Topics: Biochemistry, general

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