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5-HT4 Receptors in the Brain and Periphery

  • Book
  • © 1998

Overview

Editors:
  1. Richard M. Eglen

    1. Roche Bioscience, Palo Alto, USA

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  • The first time all aspects of the 5-HT4 receptor are covered in one book
  • Covers both basic research and clinical-therapeutic aspects

Part of the book series: Biotechnology Intelligence Unit (BIOIU)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Medicinal Chemistry of 5-HT4 Receptor Ligands

    • Robin D. Clark
    Pages 1-48

  3. Molecular Biology of 5-HT4 Receptors

    • Theresa A. Branchek, Nika Adham, Christophe Gerald
    Pages 49-61

  4. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles

    • Joël Bockaert, Aline Dumuis
    Pages 63-86

  5. Central 5-HT4 Receptors: Electrophysiology

    • Rodrigo Andrade, Samir Haj-Dahmane, Esther Chapin
    Pages 87-101

  6. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors

    • Janine M. Barnes, Nicholas M. Barnes
    Pages 103-126

  7. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors

    • Alberto J. Kaumann, Louise Sanders
    Pages 127-148

  8. 5-HT4 Receptors in Gastrointestinal Tract

    • Sharath S. Hegde
    Pages 149-169

  9. 5-HT4 Receptors in Lower Urinary Tract Tissues

    • Anthony P. D. W. Ford, M. Shannon Kava
    Pages 171-193

  10. The 5-HT4 Receptor in the Adrenal Gland

    • Hervé Lefebvre, Vincent Contesse, Catherine Delarue, Jean-Marc Kuhn, Hubert Vaudry
    Pages 195-211

  11. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists

    • Gareth J. Sanger
    Pages 213-226

  12. Back Matter

    Pages 227-229
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Keywords

About this book

This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

Editors and Affiliations

  • Roche Bioscience, Palo Alto, USA

    Richard M. Eglen

Bibliographic Information

  • Book Title: 5-HT4 Receptors in the Brain and Periphery

  • Editors: Richard M. Eglen

  • Series Title: Biotechnology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-05553-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Hardcover ISBN: 978-3-540-64164-3Published: 19 August 1998

  • Softcover ISBN: 978-3-662-05555-7Published: 14 January 2013

  • eBook ISBN: 978-3-662-05553-3Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: XIII, 229

  • Number of Illustrations: 19 b/w illustrations

  • Additional Information: Jointly published with Landes Bioscience, Georgetown, USA

  • Topics: Biochemistry, general, Neurosciences, Cell Biology, Pharmacology/Toxicology, Molecular Medicine, Animal Physiology

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