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Life Sciences - Biochemistry & Biophysics | Fundamentals of Protein Structure and Function

Fundamentals of Protein Structure and Function

Buxbaum, Engelbert

2007, XI, 367 p. With 3-D glasses.

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  • Textbook for courses at both graduate and undergraduate level
  • Also for related courses in biochemistry, biochemistry lab, and methods
  • Contains comprehensive analytical description of structure, biophysics, and function of proteins
  • Also summarizes the techniques used to characterize protein and protein interactions

 

Fundamentals of Protein Structure and Function

Engelbert Buxbaum, Dr. rer. nat.

This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic. Also covered in the text are enzymes, biocatalysts, enzyme kinetics, hemoglobin, myoglobin, prion proteins, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins into mitochondria, transport of proteins between cell compartments, transport of solutes across membranes, analytic techniques, protein-ligand interactions, protein purification, and protein structure, size and shape, emphasizing the link between protein structure, physiological function and medical significance.

 

This book is an introductory text for researchers in protein biochemistry, molecular biology, cell biology, chemistry, biophysics and biomedical research. The book also makes an ideal textbook for graduate and advanced undergraduate courses in protein structure and function, and a supplementary text for related courses.

About the Author

Dr. Buxbaum is a biochemist with interest in enzymology and protein science. Dr. Buxbaum has been working on the biochemistry of membrane transport proteins for almost 20 years and has taught courses in biochemistry and molecular medicine at several universities.

 

"The analytical descriptions of structure, biophysics and function of proteins is an extremely important aspect of today’s education in biochemistry."

Martin Sagermann, Ph.D.

University of California, Santa Barbara

Content Level » Graduate

Keywords » Amino acid - Chaperone - biochemistry - biophysics - enzyme kinetics - enzymes - protein structure - proteins

Related subjects » Biochemistry & Biophysics - Biomedical Sciences - Biophysics & Biological Physics - Cell Biology - Chemistry

Table of contents 

Protein structure.- Amino acids.- Protein structure.- Purification and characterisation of proteins.- Protein sequencing.- Enzymes.- Enzymes are biocatalysts.- Enzyme kinetics.- Haemoglobin and myoglobin: co-operativity.- Enzyme kinetics: special cases.- Special proteins.- Prion proteins and prion diseases.- Immunoproteins.- Cell skeleton.- Motor proteins and movement.- Cell-cell interactions.- Aiding in folding: molecular chaperones and chaperonins.- Membrane transport.- Transport of proteins into mitochondria.- Intracellular protein transport.- Transport of solutes across membranes.

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