Lombardini, John B., Schaffer, Stephen W., Azuma, Junichi (Eds.)
2003, XXX, 573 p.
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The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.
A Voice From the Past; J. Sturman. Dr Ralph Dawson Jr. (1954-2002).
1: Cardiovascular and Renal Effects of Taurine. 1. Inhibitory Mechanism of Taurine on the Platelet-Derived Growth Factor BB-Mediated Proliferation in Aortic Vascular Smooth Muscle Cells; K. Imada, et al. 2. Taurine on Sino-Atrial Nodal Cells: Ca2+-Dependent Modulation; H. Satoh. 3. Cellular Characterization of Taurine Transporter in Cultured Cardiac Myocytes and Nonmyocytes; T. Takatani, et al. 4. Taurine Transporter in Cultured Neonatal Cardiomyocytes: a Response to Cardiac Hypertrophy; T. Itoh, et al. 5. Effects of Taurine and Coenzyme Q10 in Patients with Acute Myocardial Infarction; R.B. Singh, et al. 2 Additional Articles.
2: Role of Taurine in Diabetes. 8. Taurine Reduces Mortality in Diabetic Rats: Taurine and Experimental Diabetes Mellitus; F. Franconi, et al. 9. The Effect of Dietary Taurine Supplementation on Plasma and Urinary Free Amino Acid Concentrations in Diabetic Rats; Young-Mi Lee, et al. 10. Insulin-Stimulated Taurine Uptake in the Rat Retina; R. Salceda. 11. The Effects of Taurine Supplementation on Patients with Type 2 Diabetes Mellitus; K.B. Chauncey, et al. 12. Hypoglycemic Effects of Taurine in the Alloxan-Treated Rabbit: a Model for Type 1 Diabetes; T.E. Tenner Jr., et al.
3: Osmoregulatory Properties of Taurine and Taurine Transport. 13. Taurine and Cellular Volume Regulation in the Hippocampus; J.E. Olson, et al. 14. Regulation of the Volume-Sensitive Taurine Efflux Pathway in NIH3T3 Mouse Fibroblasts; I.H. Lambert. 15. Taurine Counteracts Cell Swelling in Rat Cerebrocortical Slices Exposed to Ammonia in Vitro and in Vivo; R.O. Law, et al. 16. Cloning of Human Intestinal Taurine Transporter and Production of Polyclonal Antibody; Hye Suk An, et al. 10 Additional Articles.
4: Taurine Synthesis, Localization. Determination, and Nutrition. 27. Determination of Taurine and Hypotaurine in Animal Tissues by Reversed-Phase High-Performance Liquid Chromatography after Derivization with Dabsyl Chloride; H. Nakamura, T. Ubuka. 28. Immunohistochemical Localization of Taurine in the Rat Stomach; Ning Ma, et al. 29. Modulation of Taurine on CYP3A4 Induction by Rifampicin in a HepG2 Cell Line; K. Takahashi, et al. 30. Effect of Acute Ethanol Administration on S-Amino Acid Metabolism: Increased Utilization of Cysteine for Synthesis of Taurine Rather than Glutathione; Young S. Jung, et al. 31. Effects of Dietary Taurine Supplementation on Hepatic Morphological Changes of Rats in Diethynitrosamine-Induced Hepatocarcinogenesis; Kyung Ja Chang, et al. 6 Additional Articles.
5: Taurine: Growth, Antioxidants, and Inflammation. 38. Why is Taurine Cytoprotective? S. Schaffer, et al. 39. Taurine, Analogues and Bone: a Growing Relationship; R.C. Gupta, Sung-Jin Kim. 40. Anti-Inflammatory Activities of Taurine Chloramine: Implication for Immunoregulation and Pathogenesis of Rheumatoid Arthritis; E. Kontny, et al. 41. Taurine Chloramine Inhibits Production of Inflammatory Mediators and iNOS Gene Expression in Alveolar Macrophages: a Tale of Two Pathways: Part I: NF-kappa B Signaling; M.R. Quinn, et al. 42. Taurine Chloramine Inhibits Production of Inflammatory Mediators and iNOS Gene Expression in Alveolar Macrophages: a Tal