Wilson, D.F., Evans, S.M., Biaglow, J., Pastuszko, A. (Eds.)
2003, XVIII, 421 p.
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The ISOTT 2001 local organizing committee was pleased to welcome over 140 delegates from around the world to the 29th annual general meeting of the International Society for Oxygen Transport to Tissue. The meeting was held in historic Philadelphia, USA, on the campus of the University of Pennsylvania from August 11 to 15, 2001. In the tradition of ISOTT, the conference was a total immersion experience. Attendees were encouraged to eat together and spend their evenings relaxing together in a style that maximized exchange of ideas and interactions of younger scientists with their more senior colleagues. Delegates participated in a total of 122 presentations including poster displays, selected oral presentations, seminars by invited speakers and a round table discussion. In choosing invited speakers and oral presenters, special emphasis was placed on methods for oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. All of the manuscripts contained in this volume underwent both an editorial and scientific review, and only those meeting both criteria have been published. However, while all efforts have been made to eliminate editorial errors, some have undoubtedly been overlooked, for which the editors apologize.
Tumor Biology and Physiology. 1. The Role of Tumor Oxygenation in Vascular and Clinical Response to Angiogenesis Inhibition; M.S. Gee, W.M.F Lee. 2. Comparison of Fluctuations of Oxygen Tension in FSA, 9L and R3230AC Tumors in Rats; L.I. Cárdenas-Navia, et al. 3. Effect of Carbogen-Breathing on Redox Status of the RIF-1 Tumor; G. Illangovan, et al. 4. Evaluation of Microregional Variations in Tumor Hypoxia Following the Administration of Endostatin; B.M. Fenton, et al. 5. Effect of Hydralazine on Blood Flow, Oxygenation and Interstitial Fluid Pressure in Subcuataneous Tumors; T. Jarm, et al. 6. Oxygenation of Cervix Cancers: Impact of Clinical and Pathological Parameters; M. Höckel, P. Vaupel. 7. Quantitative Spatial Analysis of Hypoxia and Vascular Perfusion in Tumor Sections; T.M. Busch, et al. 8. Tumor Oxygenation and its Relevance to Tumor Physiology and Treatment; P. Vaupel, M. Höckel. 9. Mechanisms Underlying Hypoxia Developments in Tumors; M.W. Dewhirst. 10. Lack of Association Between Tumor Hypoxia, GLUT-1 Expression and Glucose Uptake in Experimental Sarcomas; O. Thews, et al. 11. The Impact of Tissue Microenvironment on Treatment Simulation; A. Dasu, J. Denekamp. 12. Evidence for and Against Hypoxia as the Primary Cause of Tumor Aggressiveness; P. Okunieff, et al. 13. Characterization of Human Gc Protein-Derived Macrophage Activation Factor (GcMAF) and its Functional Role in Macrophage Tumoricidal Activity; S.B. Mohamad, et al. Blood Physiology and Blood Substitutes. 14. Effect of HemoglobinSolutions as Hemodiluents on Capillary Oxygen Tension; R.N. Pittman, et al. 15. Different Efficacy In Vitro of Hemoglobin Based Oxygen Carriers and Red Cells; E. Bucci, et al. 16. A Novel Blood Transfusant Candidate: Intact Human Erythrocytes Containing Hemoglobin Exclusively Nitrosylated in the &agr;-Subunits; A. Tsuneshige, T. Yonetani. 17. The Contribution of Hemoglobin to Oxygen Transport in the Microcrustacean Daphnia Magna; R. Pirow. 18. Modifications of Red Blood Cell Shape and Glycoproteins Membrane Content in Septic Patients; M. Piagnerelli, et al. 19. Fiber Optic Immunosensors for Cardio-Vascular Disease Diagnosis: Quantification of Protein C, Factor V Leiden, and Cardiac Troponin T in Plasma; H.J. Kwon, et al. 20. Soft Gel Chromatography Column Analysis and Design for the Production of High Molecular Weight Blood Factors: Model Molecule Protein C; Weiwei He, D.F. Bruley. 21. Development of an Economic Miniantibody Production Process for the Purification of Protein C (Anti-Coagulant/Anti-Thrombotic); L.K. Korah, et al. Nitric Oxide Biology and Physiology. 22. Nitric Oxide Synthesis in Brain is Stimulated by Oxygen; S.R. Thom, D.G. Buerk. 23. Oxygen Indirectly Regulates Nitric Oxide Availability; P.E. James, et al. 24. Modeling the Regulation of Oxygen Consumption by Nitric Oxide; K. Lamkin-Kennard, et al. Oxygen Measurement Methods and Applications. 25. Oxygen Sensor Design: Analysis and correction of Problems Associated With Zero Current, Stability and Structure; C.J. Koch. 26. Computer Simulation of Oxygen Microelectrode Measu