Immunological Aspects

1. Front Matter

   Pages i-xv

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2. Breast-Cancer-Associated Antigens Defined by Monoclonal Antibodies

   • Michael R. Price

   Pages 1-30

3. The Immunochemistry of Some Blood Group Antigens

   • A. H. Merry, H. C. Gooi, D. Voak

   Pages 31-94

4. Molecular Characteristics of the Blood Group Rho(D) Molecule

   • Carl G. Gahmberg

   Pages 95-117

5. Expression of the ABH, Lewis, and Related Antigens on the Glycoproteins of the Human Jejunal Brush Border

   • F. R. Green, P. Greenwell, L. Dickson, B. Griffiths, J. Noades, D. M. Swallow et al.

   Pages 119-153

6. Biogenesis and Intracellular Transport of Intestinal Brush Border Membrane Hydrolases

   • Hans-Peter Hauri

   Pages 155-219

7. Immunoaffinity Purification of Membrane Fractions from Mammalian Cells

   • Peter J. Richardson, J. Paul Luzio

   Pages 221-241

8. The Use of Antibodies for Analysis of the Secretory and Endocytic Paths of Eukaryotic Cells

   • Yves Chicheportiche, Alan Michael Tartakoff

   Pages 243-275

9. Monoclonal Antibodies in Investigations on Astrocytes

   • S. K. Malhotra

   Pages 277-306

10. Current Molecular Approaches to Experimental Thyroid Autoimmunity

    • Brian R. Champion, Patricia Hutchings, Anne Cooke, Kevin Page, Gopa Biswas-Hughes, Humberto Assis de Paiva et al.

    Pages 307-333

11. Biochemistry and Pathophysiology of the Molecular Forms of Cholinesterases

    • Zoltán Rakonczay, Stephen Brimijoin

    Pages 335-378

12. Back Matter

    Pages 379-384

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This volume and future ones in the series, which is now under new editorship. depart from the pattern established by previous volumes in containing chapters loosely related to one another. It is thus appropriate that each volume should have a relevant subtitle. In the present volume the underlying theme is immu­ nology and its application to the study of a number of different biochemical systems. Almost inevitably, the study of the cell-surface antigens and glycoproteins of a number of different tissues tends to dominate the contents, but considerable emphasis is also placed on subcellular organelles and enzymes. Undoubtedly, it is the impact of readily available monoclonal antibodies that dominates work in the field. The epitope specificity provided by monoclonal antibodies gives the biochemist a powerful lever with which to probe the location, structure, and function of cellular protein and glycoprotein antigens. A number of the chapters included in this volume have a strong biomedical emphasis. This is indeed intentional, as it is now the policy of the series to cover the more applied aspects ofthe subject, while in no way neglecting more fundamentaltopics in subcellular biochemistry.

• Organe
• biochemistry
• enzymes
• proteins
• tissue

• North East Thames Regional Transfusion Centre, Brentwood, Essex, England

  J. R. Harris

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