Editors:
- Provides a collection of robust protocols for molecular biologists studying comparative genomics
- Each chapter includes detailed instructions for using a particular tool or method and an introduction to the theory behind the technique
- A Notes section at the end of each chapter that guides the user through commonly encountered difficulties, providing key tips for using the method most efficiently
Part of the book series: Methods in Molecular Biology (MIMB, volume 396)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (27 protocols)
-
Front Matter
-
Comparative Analysis of Domain and Protein Families
-
Front Matter
-
-
Orthologs, Synteny, and Genome Evolution
-
Front Matter
-
-
Experimental Analysis of Whole Genomes: Analysis of Copy Number and Sequence Polymorphisms
-
Front Matter
-
About this book
Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press.
Editors and Affiliations
-
Bioinformatics Program and Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor
Nicholas H. Bergman
Bibliographic Information
Book Title: Comparative Genomics
Book Subtitle: Volume 2
Editors: Nicholas H. Bergman
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-515-2
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2007
Hardcover ISBN: 978-1-934115-37-4
Softcover ISBN: 978-1-61737-933-8
eBook ISBN: 978-1-59745-515-2
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVIII, 434
Number of Illustrations: 150 b/w illustrations, 1 illustrations in colour
Topics: Biochemistry, general, Human Genetics, Cell Biology