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ARF Family GTPases

  • Book
  • © 2003

Overview

Authors:
  1. Richard A. Kahn

    1. Emory University School of Medicine, Atlanta, USA

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Part of the book series: Proteins and Cell Regulation (PROR, volume 1)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xxviii
    Download chapter PDF

  2. The Arf Family Tree

    • John M. Logsdon Jr., Richard A. Kahn
    Pages 1-21

  3. The GDP/GTP Cycle of Arf Proteins

    • Sebastiano Pasqualato, Louis Renault, Jacqueline Cherfils
    Pages 23-48

  4. Arf and Phospholipids

    • Paul A. Randazzo, Zhongzhen Nie, Dianne S. Hirsch
    Pages 49-69

  5. The Sec7 Family of Arf Guanine Nucleotide Exchange Factors

    • Catherine L. Jackson
    Pages 71-99

  6. Large Arf GEFs of the Golgi Complex

    • Paul Melançon, Xinhua Zhao, Troy K. R. Lasell
    Pages 101-119

  7. BIG1 and BIG2: Brefeldin A-Inhibited Exchange Factors for Arfs

    • G. Pacheco-Rodriguez, J. Moss, M. Vaughan
    Pages 121-135

  8. Arf GTPase-Activating Protein 1

    • Dan Cassel
    Pages 137-157

  9. GIT Proteins: Arf Gaps and Signaling Scaffolds

    • Robert Schmalzigaug, Richard Premont
    Pages 159-183

  10. Paxillin-Associated Arf GAPs

    • Hisataka Sabe
    Pages 185-207

  11. Activation of Cholera Toxin and E. Coli Heat-Labile Enterotoxin (LT) by Arf

    • G. Pacheco-Rodriguez, Naoko Morinaga, Masatoshi Noda, J. Moss, M. Vaughan
    Pages 209-222

  12. Phospholipase D, Arfaptins and Arfophilin

    • John H. Exton
    Pages 223-240

  13. Coat Proteins

    • Annette Boman, Tommy Nilsson
    Pages 241-257

  14. Heterotetrameric Coat Protein-Arf Interactions

    • M. L. Styers, V. Faundez
    Pages 259-281

  15. Arf6

    • James E. Casanova
    Pages 283-303

  16. A Role for Arf6 in G Protein-coupled Receptor Desensitization

    • Mary Hunzicker-Dunn
    Pages 305-324

  17. Arf-Like Proteins

    • Annette Schürmann, Hans-Georg Joost
    Pages 325-350
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Keywords

About this book

For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing them in detail are provided. The impact of the ARF proteins on widely diverse aspects of cell biology and cell signalling can be clearly seen from the activities described; including membrane traffic, lipid metabolism, receptor desensitization, mouse development, microtubule dynamics, and bacterial pathogenesis. Anyone interested in understanding the complexities of cell signalling and the integration of signalling networks will benefit from this volume.

Reviews

From the reviews:

"A journey into a deeper understanding of the diversity of cellular controls exerted by the ARF family. The writing is so clear and well developed … it will allow newcomers in the area to dive into a dynamic area of molecular and cellular science. … the reader is treated to a wealth of discussion and critique on how ARFs modulate processes such as membrane fusion, vesicular transport, cell migration and receptor activity. This is an outstanding text for everyone with an interest in cell biology." (M. Thompson, Cell Biochemistry and Function, Vol. 23 (4), 2005)

Authors and Affiliations

  • Emory University School of Medicine, Atlanta, USA

    Richard A. Kahn

Bibliographic Information

  • Book Title: ARF Family GTPases

  • Authors: Richard A. Kahn

  • Series Title: Proteins and Cell Regulation

  • DOI: https://doi.org/10.1007/1-4020-2593-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2003

  • Hardcover ISBN: 978-1-4020-1719-3Published: 29 February 2004

  • Softcover ISBN: 978-90-481-6469-1Published: 30 December 2010

  • eBook ISBN: 978-1-4020-2593-8Published: 11 April 2006

  • Series ISSN: 1567-2530

  • Series E-ISSN: 2542-9973

  • Edition Number: 1

  • Number of Pages: XXVIII, 350

  • Number of Illustrations: 51 b/w illustrations

  • Topics: Biochemistry, general, Evolutionary Biology

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