Formation of the Heart and its Regulation

1. Front Matter

   Pages i-xv

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2. Overview of Heart Development

   • Roger R. Markwald, Andy Wessels

   Pages 1-22

3. Myofibrillogenesis in the Heart

   • Carol C. Gregorio, Parker B. Antin

   Pages 23-43

4. Cardiac Looping and the Left-Right Axis: Integrating Morphologic, Molecular, and Genetic Analyses of Vertebrate Left-Right Asymmetry

   • Ann F. Colli, H. Joseph Yost

   Pages 45-73

5. Differentially Expressed Genes and Cardiac Morphogenesis

   • Jim J.-C. Lin, Da-Zhi Wang, Rebecca S. Reiter, Qin Wang, Jenny J. -C. Lin, Haley S. Williams

   Pages 75-96

6. Molecular Mechanisms of Cardiac Diversification

   • Jeffrey D. Croissant, Stacey Carpenter, David Bader

   Pages 97-108

7. Neural Crest and Heart Development

   • Margaret L. Kirby

   Pages 109-120

8. Cardiac Conduction System Development

   • Takashi Mikawa, Robert G. Gourdie, Jeanette Hyer, Kimiko Takebayashi-Suzuki

   Pages 121-135

9. The Epicardium and the Formation of the Coronary Vasculature

   • Robert E. Poelmann, F Pau Mark, M Vrancken Peeters, Adriana C Gittenberger-deGroot

   Pages 137-145

10. The Role of the Extracellular Matrix and Its Receptors in Modulating Cardiac Development

    • Edie C. Goldsmith, Wayne Carver, Thomas K. Borg

    Pages 147-169

11. Growth Factor Regulation of Embryonic, Fetal, and Neonatal Cardiac Development

    • Robert L. Price, Jay D. Potts, Thomas E. Thielen, Thomas K. Borg, Louis Terracio

    Pages 171-199

12. Transforming Growth Factor-β Signal Transduction in the Atrioventricular Canal During Heart Development

    • Angelique S. Boyer, Raymond B. Runyan

    Pages 201-219

13. Homocysteine and the N-Methyl-D-Aspartate (NMDA) Receptor: Are They Keys to Conotruncal Abnormalities?

    • Thomas H. Rosenquist, Daniel T. Monaghan

    Pages 221-249

14. Function and Biomechanics of Developing Cardiovascular Systems

    • Bradley B. Keller

    Pages 251-271

15. Back Matter

    Pages 273-276

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The `Formation of the Heart and its Regulation` reviews in considerable detail the major events in heart development and their control via genes, cell-cell interactions, growth factors and other contributing elements. In addition, there is an extensive and useful overview of the field of heart development taken as a whole. The book will appeal to all students and researchers working on cardiovascular development and to pediatric cardiologists.

• biomechanics
• cardiac development
• cardiovascular
• cardiovascular system
• development
• genes
• growth
• heart
• molecular mechanisms
• morphogenesis
• regulation
• signal transduction
• system

• Department of Anatomy and Cell Biology, University of Iowa, Iowa City, USA

  Robert J. Tomanek

• Department of Cell Biology and Anatomy, University of Arizona, Tucson, USA

  Raymond B. Runyan

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