1995, LX, 1212 p. In 2 volumes, not available separately.
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Animal cell technology is a discipline of growing importance, which aims not merely at understanding structure, function and behaviour of differentiated animal cells, but especially at the development of their abilities useful for clinical application. Topics of interest in this regard include: viral vaccines, pharmaceutical proteins and novel applications such as gene therapy and organ culture. Undoubtedly, these Proceedings of the joint Meeting of the European Society for Animal Cell Technology and the Japanese Association for Animal Cell Technology (Veldhoven, The Netherlands, September 1994) review the most recent status of the field, and will be most valuable to anyone actively involved in the culture of animal cells and its applications. The contributions to this volume were strictly selected on the basis of quality and novelty of contents. Kluwer is honoured to be able to add this work to its strongly developing publication programme in cell and tissue culture, which now has its connections to all major Societies in this field worldwide. Audience: Cell biologists, biochemists, molecular biologists, immunologists, virologists and all other disciplines related to animal cell technology, working in an academic environment, as well as in (biotechnology or pharmaceutical) industry.
I: Establishment of production cell lines; cloning and selection strategies. II: Conditions for high performance cultures for the production of biologicals. III: Protein processing. IV: Protein (monoclonal antibody) engineering. V: Regulatory issues, safety and containment. VI: Animal-cell bioreactors: design and scale-up considerations. VII: New developments: clinical studies, tissue engineering, apoptosis and novel applications.