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Molecular and Cell Biology of Muscular Dystrophy gives a series of accounts of various aspects of the remarkable breakthrough which has been achieved in our understanding of the Duchenne/Becker muscular dystrophies and of the consequences and ramifications of this breakthrough.
Molecular human genetics and the Duchenne/Becker muscular dystrophy gene. Genotype/phenotype correlations in Duchenne/Becker dystrophy. Molecular genetics and genetic counselling for Duchenne/Becker muscular dystrophy. Inheritance and pathogenicity of myotonic dystrophy. Genetic mapping of facioscapulohumeral muscular dystrophy. Dystrophin-associated glycoproteins: their possible roles in the pathogenesis of muscular dystrophy. PCR analysis of muscular dystrophy in mdx mice. Cell biology of the satellite cell. Molecular and cell biology of skeletal muscle regeneration. Molecular mechanisms of muscle damage. Human dystrophin gene transfer: genetic correction of dystrophin deficiency. Myoblast transplantation in inherited myopathies.