Mediastinal Lesions

1. Front Matter

   Pages i-xii

   PDF

2. Introduction

   • Frank Detterbeck

   Pages 1-3

3. Mediastinal Biopsy Techniques

   • Robert J. Korst

   Pages 5-24

4. Radiologic Features of Mediastinal Lesions

   • Brett W. Carter, Edith M. Marom

   Pages 25-50

5. Cytologic Features of Mediastinal Lesions

   • Andre L. Moreira

   Pages 51-86

6. Thymic Epithelial Tumors and Benign Thymic Lesions

   • Alexander Marx, Cleo-Aron Weis, Alexandar Tzankov, Philipp Ströbel

   Pages 87-148

7. Mediastinal Germ Cell Tumors

   • Anja C. Roden

   Pages 149-172

8. NUT Carcinoma

   • Lucian R. Chirieac, Christopher A. French

   Pages 173-187

9. Lymphomas of the Thymus and Mediastinum

   • Philipp Ströbel, Alexander Marx

   Pages 189-216

10. Non-neoplastic/Inflammatory Lesions in the Mediastinum

    • Eunhee S. Yi

    Pages 217-231

11. Soft Tissue Tumors of the Mediastinum

    • Narasimhan P. Agaram

    Pages 233-255

12. Summary

    • Andre L. Moreira, Anja C. Roden

    Pages 257-260

13. Back Matter

    Pages 261-271

    PDF

This book addresses the current concepts in tissue acquisition, diagnosis, and classification of mediastinal lesions in small biopsies including cytology. Examples of mediastinal diseases that are either more common, more challenging to diagnose, or have a differential diagnosis that is important and might require different modes of treatment are highlighted. The knowledge of some key morphologic features and immunohistochemical pitfalls will be helpful for the practicing pathologist to tackle this challenge. The general workup of a mediastinal biopsy and the workup of major disease groups in mediastinal pathology which the general pathologist should be familiar with is discussed. Morphologic and, if applicable, immunophenotypic and molecular features that can help to distinguish these disease entities are highlighted. Furthermore, the reader will learn about the pertinent clinical implications of the diseases. Mediastinal Lesions: Diagnostic Pearls for Interpretation of SmallBiopsies and Cytology will be a reference guide for pathologists, pathologists-in-training, and allied professionals, including oncologists, pulmonologists, surgeons, and radiologists. 

• Mediastinal cysts
• NUT midline carcinomas
• Non-neoplastic/inflammatory lesions
• Posterior mediastinum
• Thymic lesions

• Department of Pathology, Mayo Clinic School of Medicine, Rochester, USA

  Anja C. Roden

• Department of Pathology, New York University Langone Medical Center, New York, USA

  Andre L. Moreira

Anja C. Roden, MD


Associate Professor and Consultant of Pathology


Mayo Clinic College of Medicine


Rochester, MN 55905


USA




Andre L. Moreira, MD, PhD


Associate Attending of Pathology


Memorial Sloan Kettering Cancer Center


New York, NY 10065


USA

Policies and ethics