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  • © 2016

Gene Expression Systems in Fungi: Advancements and Applications

  • We bring together articles of experienced and renowned experts and highlight diverse aspects of gene expression systems of fungi
  • We will cover a broad array of topics from industrial requirements to recent advancements and novel solutions
  • The book shall provide a balanced view of advantages for fungal biotechnology and the appropriate systems for the respective applications
  • Includes supplementary material: sn.pub/extras

Part of the book series: Fungal Biology (FUNGBIO)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xv
  2. Organisms

    1. Front Matter

      Pages 1-1
    2. Gene Expression Systems in Industrial Ascomycetes: Advancements and Applications

      • Jonas Ramoni, Verena Seidl-Seiboth, Robert H. Bischof, Bernhard Seiboth
      Pages 3-22
    3. Production of Industrial Enzymes in Trichoderma reesei

      • Marja Paloheimo, Thomas Haarmann, Susanna Mäkinen, Jari Vehmaanperä
      Pages 23-57
    4. Improvement of Industrially Relevant Biological Activities in Mucoromycotina Fungi

      • Tamás Papp, Ildikó Nyilasi, Árpád Csernetics, Gábor Nagy, Miklós Takó, Csaba Vágvölgyi
      Pages 97-118
    5. Homologous and Heterologous Expression of Basidiomycete Genes Related to Plant Biomass Degradation

      • Sara Casado López, Outi-Maaria Sietiö, Kristiina Hildén, Ronald P. de Vries, Miia R. Mäkelä
      Pages 119-160
    6. The Corn Smut Fungus Ustilago maydis as an Alternative Expression System for Biopharmaceuticals

      • Parveen Sarkari, Michael Feldbrügge, Kerstin Schipper
      Pages 183-200
    7. Yeast Expression Systems for Industrial Biotechnology

      • Pramote Chumnanpuen, Kanokarn Kocharin, Wanwipa Vongsangnak
      Pages 227-237
  3. Tools

    1. Front Matter

      Pages 239-239
    2. High-Throughput Construction of Genetically Modified Fungi

      • Gyungsoon Park, Shouqiang Ouyang, Katherine A. Borkovich
      Pages 241-252
    3. Awakening of Fungal Secondary Metabolite Gene Clusters

      • Juliane Fischer, Volker Schroeckh, Axel A. Brakhage
      Pages 253-273
    4. Understanding the Mechanism of Carbon Catabolite Repression to Increase Protein Production in Filamentous Fungi

      • Daniel Kiesenhofer, Astrid R. Mach-Aigner, Robert L. Mach
      Pages 275-288
    5. Inteins and Their Use in Protein Synthesis with Fungi

      • Skander Elleuche, Stefanie Pöggeler
      Pages 289-307
    6. Relevance of Signal Transduction Pathways for Efficient Gene Expression in Fungi

      • Eva Stappler, Aroa Rodriguez-Iglesias, Hoda Bazafkan, Guofen Li, Monika Schmoll
      Pages 309-334
    7. Sexual Development in Fungi and Its Uses in Gene Expression Systems

      • George D. Ashton, Paul S. Dyer
      Pages 335-350

About this book

Biotechnology has emerged as one of the key environmentally safe technologies for the future which enables use of biomass to develop novel smart materials and to replace oil derived products. Fungi are the most efficient producers of the enzymes needed for this purpose and in addition they produce a plethora of secondary metabolites, among which novel antibiotics can be found. Industrial application and exploitation of the metabolic capacities of fungi requires highly productive and robust gene expression systems, which can be achieved by selection of appropriate species and strain improvement. In this book we aim to summarize homologous and heterologous gene expression systems of fungi for production of enzymes and secondary metabolites. A broad overview on requirements, challenges and successful applications shall serve as a basis for further development of fungi as biotechnological workhorses in research and industry.

Reviews

     

Editors and Affiliations

  • and Environment-Bioresources, AIT Austrian Institute of Technology Department of Health, Tulln, Australia

    Monika Schmoll, Christoph Dattenböck

About the editors

Dr. Monika Schmoll received her degree and Ph. D. on the topic of “Regulation of cellulase expression and signal transduction in the filamentous fungus Hypocrea jecorina (Trichoderma reesei)” at the Vienna University of Technology, Austria. Besides gaining postdoctoral experience and building her own group at the Vienna University of Technology, she has been a visiting scientist in the laboratory of Professor N. Louise Glass (Department of Plant and Microbial Biology, University of California, Berkeley, USA), the University of Rome La Sapienza and the University of Szeged, Hungary. In 2012, Dr. Schmoll moved to the Austrian Institute of Technology (AIT) in Tulln, Austria, where she is now group leader and senior scientist. In march 2013 she completed her habilitation at the Vienna University of Technology in the field of “Molecular Genetics and Genomics”.

The primary research field of Dr. Schmoll is the interconnection between light response, sexual development and metabolism, with an emphasis on effects on cellulase gene expression in the filamentous fungus Trichoderma reesei. She showed for the first time that cellulase gene expression is modulated by light in T. reesei and could since then elucidate important mechanistic details on the underlying mechanism. Her group discovered the sexual cycle in the biotechnological workhorseTrichoderma, which had previously been considered asexual. Recently, her group also showed that communication upon sexual development is mediated by regulation of secondary metabolism. Her work with Trichoderma is complemented by contributions to genome annotation of several fungi (Trichoderma spp., Aspergillus nidulans, Postia placenta, Ceriporiopsis subvermispora, Phlebiopsis gigantea), especially in the field of signal transduction.   

Bibliographic Information

  • Book Title: Gene Expression Systems in Fungi: Advancements and Applications

  • Editors: Monika Schmoll, Christoph Dattenböck

  • Series Title: Fungal Biology

  • DOI: https://doi.org/10.1007/978-3-319-27951-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-27949-7Published: 11 April 2016

  • Softcover ISBN: 978-3-319-80245-9Published: 25 April 2018

  • eBook ISBN: 978-3-319-27951-0Published: 04 April 2016

  • Series ISSN: 2198-7777

  • Series E-ISSN: 2198-7785

  • Edition Number: 1

  • Number of Pages: XV, 499

  • Number of Illustrations: 19 b/w illustrations, 19 illustrations in colour

  • Topics: Biotechnology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access