175 years of Springer publishing +++ Limited offer: Any eBook in the Springer Archives 9.99 each!

Methods in Molecular Biology

Genome-Wide Association Studies and Genomic Prediction

Editors: Gondro, Cedric, van der Werf, Julius, Hayes, Ben (Eds.)

  • Examines genome-wide association studies, from the preliminary issues to statistical approaches and more
  • Features detailed, step-by-step instruction
  • Includes tips and expert implementation advice to ensure successful results
see more benefits

Buy this book

eBook $149.00
price for Mexico (gross)
  • ISBN 978-1-62703-447-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for Mexico
  • ISBN 978-1-62703-446-3
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for Mexico
  • ISBN 978-1-4939-5964-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations.  Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information.  Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study.  The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation.  Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.

Reviews

From the reviews:

“A detailed review that will help both genomics newbies and experts to have a better picture of what their genome sequences can offer them today. … People working in medicine and health sciences should read this book and get involved in the field. … anyone unfamiliar with the topic, but with the desire to learn more about what they could find in their own genome, can start learning from scratch by reading this book.” (Alejandra Manjarrez, Lab Times, Issue 5, September, 2013)

“A practical guide for experts to obtain, qualify, and statistically analyse data on genomes and to support genotype-phenotype information. In a growing field, this is the first hands-on book for experts in a relatively new discipline. … the book is too good to ignore once you start reading and pick up information along the way. … if you are new to the field, this book will certainly extend you a warm welcome to the tricky world of GWAS.” (Vijay Shankar, Lab Times, Issue 6, 2013)


Table of contents (26 chapters)

  • R for Genome-Wide Association Studies

    Gondro, Cedric (et al.)

    Pages 1-17

  • Descriptive Statistics of Data: Understanding the Data Set and Phenotypes of Interest

    Dominik, Sonja

    Pages 19-35

  • Designing a GWAS: Power, Sample Size, and Data Structure

    Ball, Roderick D.

    Pages 37-98

  • Managing Large SNP Datasets with SNPpy

    Mitha, Faheem

    Pages 99-127

  • Quality Control for Genome-Wide Association Studies

    Gondro, Cedric (et al.)

    Pages 129-147

Buy this book

eBook $149.00
price for Mexico (gross)
  • ISBN 978-1-62703-447-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for Mexico
  • ISBN 978-1-62703-446-3
  • with online files
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for Mexico
  • ISBN 978-1-4939-5964-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Genome-Wide Association Studies and Genomic Prediction
Editors
  • Cedric Gondro
  • Julius van der Werf
  • Ben Hayes
Series Title
Methods in Molecular Biology
Series Volume
1019
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-62703-447-0
DOI
10.1007/978-1-62703-447-0
Hardcover ISBN
978-1-62703-446-3
Softcover ISBN
978-1-4939-5964-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 566
Number of Illustrations and Tables
36 b/w illustrations, 31 illustrations in colour
Topics