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  • © 2016

Rodent Model as Tools in Ethical Biomedical Research

  • Information for researchers of different fields which uses rodents as experimental models

  • Discuss all the ethics aspects involved in procedures with laboratory animals facing negative stereotypes of research with rodents

  • Accessible language, undergraduate students can easily comprehend

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xvii
  2. Ethics

    1. Front Matter

      Pages 1-1
    2. Introduction

      • Monica Levy Andersen
      Pages 3-6
    3. Care and Maintenance of Laboratory Animals

      • Monica Levy Andersen, Vânia D’Almeida, Gui Mi Ko, Paulo José Forcina Martins, Sergio Tufik
      Pages 23-37
    4. Euthanasia

      • Monica Levy Andersen, Vera Baumans
      Pages 39-49
  3. Use of Rats

    1. Front Matter

      Pages 51-51
    2. The Health of Laboratory Animals

      • Monica Levy Andersen, Vânia D’Almeida, Gui Mi Ko, Paulo José Forcina Martins, Sergio Tufik
      Pages 53-60
    3. Rats

      • Monica Levy Andersen, Renata Mázaro e Costa, Marcos Fernando Oliveira e Costa
      Pages 61-94
    4. The Female Rat

      • Isabela Beleza Antunes, Andressa da Silva, Regiane Kawakami, Monica Levy Andersen
      Pages 95-109
  4. General Procedures and Methods in Rodents Research

    1. Front Matter

      Pages 111-111
    2. Anaesthesia in Laboratory Animals

      • René Remie
      Pages 113-127
    3. Various Surgical Procedures in Rodents

      • René Remie
      Pages 129-168
    4. Transgenic Animals: Principles, Methods and Applications

      • Suzana Macedo de Oliveira, Heloisa Allegro Baptista, João Bosco Pesquero
      Pages 169-185
    5. Gene Expression Studies Using Microarrays

      • Camila Guindalini, Renata Pellegrino
      Pages 203-216
    6. Brain Microdialysis

      • Carlos Eduardo Antunes de Macedo, Gabriel Cuadra, Sergé Gobaille, Luiz Eugênio Araújo de Moraes Mello
      Pages 217-233
  5. Behavioral Models in Rodents

    1. Front Matter

      Pages 235-235
    2. Sexual Behavior in Rats: An Animal Model for the Study of the Neuroendocrine System

      • M. Jennifer Rodriguez, Tathiana Aparecida Fernandes Alvarenga, Edith Monroy-López, Armando Ferreira-Nuño, Adriana Morales-Otal, Javier Velázquez-Moctezuma
      Pages 237-251

About this book

​The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.

Editors and Affiliations

  • Department of Psychobiology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

    Monica Levy Andersen, Sergio Tufik

About the editors

Professor Monica Levy Andersen is Master in Psychobiology and PhD in Psychobiology by Universidade Federal de São Paulo, UNIFESP, Post Doctoral Fellow at Division of Neuroscience Yerkes National Primate Research Center - Emory University. Professor of Division of Sleep at Department of Psychobiology of Universidade Federal de São Paulo (UNIFESP). Visiting Professor of Division of Neuropharmacology at Yerkes National Primate Research Center - Emory University and Division of Neurosciences of New England Primate Research Center - Harvard Medical School. Professor Sergio Tufik is Master in Physiology and PhD in Pharmacology by Universidade Federal de São Paulo, UNIFESP. Full professor of Division of Sleep at Department of Psychobiology of Universidade Federal de São Paulo, UNIFESP.

Bibliographic Information

  • Book Title: Rodent Model as Tools in Ethical Biomedical Research

  • Editors: Monica Levy Andersen, Sergio Tufik

  • DOI: https://doi.org/10.1007/978-3-319-11578-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-11577-1Published: 04 December 2015

  • Softcover ISBN: 978-3-319-79171-5Published: 27 March 2019

  • eBook ISBN: 978-3-319-11578-8Published: 26 November 2015

  • Edition Number: 1

  • Number of Pages: XVII, 516

  • Number of Illustrations: 57 b/w illustrations, 137 illustrations in colour

  • Topics: Neurosciences, Behavioral Sciences

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access