Overview
Provides a comprehensive review of diagnosis and treatments of renal cell carcinoma
Presents the most recent advances in molecular bases and targeted therapy for renal cell carcinoma
Contains important information about pharmacokinetics and pharmacodynamics in molecular- targeted agents of renal cell carcinoma
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Table of contents (16 chapters)
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Front Matter
Keywords
About this book
This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct from other types of solid neoplasms. In the past decade, however, treatment options for RCC have been expanding and moving quickly toward laboratory-based and molecular-targeted therapies. Advances in RCC therapy also have brought novel treatment options to other types of cancer, such as a TKI for hepatocellular carcinoma and gastrointestinal tumors, as well as mTOR inhibitors to progressive neuroendocrine tumors of pancreatic origin and to breast cancer, suggesting that RCC is no longer an "orphan disease" in the field of molecular oncology. Additional topics covered in the book include pharmacokinetics and pharmacodynamics in molecular-targeted agents and the putative mechanism of resistance to anti-angiogenic agents, such as intratumoral heterogeneity or cancer stem cell population. This volume provides the latest and most useful information for all readers who are eagerly devoted to curing renal cell carcinoma.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Renal Cell Carcinoma
Book Subtitle: Molecular Features and Treatment Updates
Editors: Mototsugu Oya
DOI: https://doi.org/10.1007/978-4-431-55531-5
Publisher: Springer Tokyo
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Japan KK 2017
License: CC BY
Hardcover ISBN: 978-4-431-55530-8Published: 22 February 2017
Softcover ISBN: 978-4-431-56661-8Published: 19 July 2018
eBook ISBN: 978-4-431-55531-5Published: 14 February 2017
Edition Number: 1
Number of Pages: X, 381
Number of Illustrations: 24 b/w illustrations, 54 illustrations in colour
Topics: Oncology, Urology, Molecular Medicine