Amorphous Drugs

Benefits and Challenges

Authors: Rams-Baron, M., Jachowicz, R., Boldyreva, E., Zhou, D., Jamroz, W., Paluch, M.

  • Offers a comprehensive review on fundamental concepts and recent advances in the field of amorphous pharmaceuticals
  • World-leading specialists from different fields present their perspectives on amorphous drugs
  • Introduces to both fundamental physical aspects and preparation and formulation methods
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書籍の購入

イーブック 95,19 €
価格の適用国: Japan (小計)
  • ISBN 978-3-319-72002-9
  • ウォーターマーク付、 DRMフリー
  • ファイル形式: EPUB, PDF
  • どの電子書籍リーダーからでもすぐにお読みいただけます。
  • ご購入後、すぐにダウンロードしていただけます。
ハードカバー 114,99 €
価格の適用国: Japan (小計)
  • ISBN 978-3-319-72001-2
  • 個人のお客様には、世界中どこでも配送料無料でお届けします。
  • Usually dispatched within 3 to 5 business days.
この書籍について

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. 

Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

著者について

Dr. Marzena Rams-Baron holds an assistant professor position in the Department of Biophysics and Molecular Physics at University of Silesia in Katowice.

Prof. Dr. Renata Jachowicz is currently head of the Chair and Department of Pharmaceutical Technology and Biopharmaceutics at Jagiellonian University in Cracow. She is a member of Committee on Therapy and Drug Research of the Polish Academy of Science, Head of Subcommittee of Pharmaceutical Technology and Biopharmacy and also Head of the Expert Group of Pharmaceutical Technology and Galens Products of Polish Pharmacopoeia Committee.

Prof. Dr. Elena Boldyreva is a Chief Researcher at the Institute of Solid State Chemistry and Mechanochemistry, Siberian Branch of Russian Academy of Sciences in Novosibirsk and the Head of the Chair of Solid State Chemistry of Novosibirsk State University.

Dr. Deliang Zhou  is a principal research pharmaceutical scientist in Drug Products, Operations Science & Technology at AbbVie. 

Dr. Witold Jamróz holds an assistant professor position in the Department of Pharmaceutical Technology and Biopharmaceutics at Jagiellonian University in Cracow

Prof. Dr. Marian Paluch is currently the head of the Department of Biophysics and Molecular Physics at University of Silesia in Katowice. Since 2010 he is an academic editor in AIP Advances. He is (co)author of more than 380 publications, a book and several book chapters. His papers were cited more than 7700 times.

Table of contents (6 chapters)

  • Why Amorphous Drugs?

    Rams-Baron, Marzena (et al.)

    Pages 1-7

    Preview Buy Chapter 26,95 €
  • Order vs. Disorder in the Solid State

    Rams-Baron, Marzena (et al.)

    Pages 9-39

    Preview Buy Chapter 26,95 €
  • Amorphous Drug Solubility and Absorption Enhancement

    Rams-Baron, Marzena (et al.)

    Pages 41-68

    Preview Buy Chapter 26,95 €
  • Amorphous Drug Preparation Methods

    Rams-Baron, Marzena (et al.)

    Pages 69-106

    Preview Buy Chapter 26,95 €
  • Physical Instability: A Key Problem of Amorphous Drugs

    Rams-Baron, Marzena (et al.)

    Pages 107-157

    Preview Buy Chapter 26,95 €

書籍の購入

イーブック 95,19 €
価格の適用国: Japan (小計)
  • ISBN 978-3-319-72002-9
  • ウォーターマーク付、 DRMフリー
  • ファイル形式: EPUB, PDF
  • どの電子書籍リーダーからでもすぐにお読みいただけます。
  • ご購入後、すぐにダウンロードしていただけます。
ハードカバー 114,99 €
価格の適用国: Japan (小計)
  • ISBN 978-3-319-72001-2
  • 個人のお客様には、世界中どこでも配送料無料でお届けします。
  • Usually dispatched within 3 to 5 business days.
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書誌情報

Bibliographic Information
Book Title
Amorphous Drugs
Book Subtitle
Benefits and Challenges
Authors
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
イーブック ISBN
978-3-319-72002-9
DOI
10.1007/978-3-319-72002-9
ハードカバー ISBN
978-3-319-72001-2
Edition Number
1
Number of Pages
IX, 230
Number of Illustrations and Tables
21 b/w illustrations, 48 illustrations in colour
Topics