Molecular Biomedicine - Virtual Issue: Tumor Pathophysiology & Biomarkers
It is reported by WHO that Cancer is the second leading cause of death globally, accounting for an estimated 9.6 million deaths, or one in six deaths. Almost 30% - 50% of cancer deaths could be prevented by modifying or avoiding key risk factors and implementing existing evidence-based prevention strategies. Cancer is more likely to respond to effective treatment when identified earlier, resulting in a greater probability of surviving as well as less morbidity and less expensive treatment.
This collection features papers on key topics in cancer research, and specifically focuses on Tumor Pathophysiology & Biomarkers in this particular issue. All articles have been published and are free to read online. Articles will undergo all of the journal's standard peer review and editorial processes outlined in its submission guidelines. (this opens in a new tab)
Progress in exosome associated tumor markers and their detection methods
Shen, M., Di, K., He, H. et al.
https://link.springer.com/article/10.1186/s43556-020-00002-3 (this opens in a new tab)
Revisiting cancer hallmarks: insights from the interplay between oxidative stress and non-coding RNAs
Zhou, L., Zhang, Z., Huang, Z. et al.
https://link.springer.com/article/10.1186/s43556-020-00004-1 (this opens in a new tab)
cGAS/STING: novel perspectives of the classic pathway
Gao, M., He, Y., Tang, H. et al.
https://link.springer.com/article/10.1186/s43556-020-00006-z (this opens in a new tab)
RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers
Alblihy, A., Alabdullah, M.L., Toss, M.S. et al.
https://link.springer.com/article/10.1186/s43556-020-00023-y (this opens in a new tab)
Checkpoint Kinase 1 (Chk1) inhibition fails to activate the Stimulator of Interferon Genes (STING) innate immune signaling in a human coculture cancer system
Brooks, T., Wayne, J. & Massey, A.J.
https://link.springer.com/article/10.1186/s43556-021-00044-1 (this opens in a new tab)
Post-translational modifications of CDK5 and their biological roles in cancer
Gao, GB., Sun, Y., Fang, RD. et al.
https://link.springer.com/article/10.1186/s43556-021-00029-0 (this opens in a new tab)
Scientific and clinical implications of genetic and cellular heterogeneity in uveal melanoma
de Lange, M.J., Nell, R.J. & van der Velden, P.A.
https://link.springer.com/article/10.1186/s43556-021-00048-x (this opens in a new tab)
Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer
Bollig-Fischer, A., Bao, B., Manning, M. et al.
https://link.springer.com/article/10.1186/s43556-021-00051-2 (this opens in a new tab)
Detection of alternative lengthening of telomeres mechanism on tumor sections
Wang, Y., Yang, H., Li, H. et al.
https://link.springer.com/article/10.1186/s43556-021-00055-y (this opens in a new tab)