Pflügers Archiv - European Journal of Physiology - Call for Papers - Oxygen Sensors

Pflügers Archiv – Special issue

Oxygen Sensors – HIF-Hydroxylases in Physiology, Pathophysiology and Pharmacology

The cellular response to life-threatening lack of oxygen, hypoxia, has stimulated physiologist to study oxygen sensing in cells and tissue. The discovery of the transcription factor hypoxia inducible factor (HIF) and how cells sense oxygen availability through HIF-hydroxylases was awarded with the Nobel Prize 2019 in Physiology or Medicine to Gregg L. Semenza, Sir Peter J. Ratcliffe and William G. Kaelin Jr. We now encourage contributions on cellular hypoxic responses that go beyond the classical HIF-dependent transcription. We invite you to contribute to our special issue by original reports or overview articles how hypoxic-inducible factor (HIF) hydroxylases are affected in physiology, e.g. by hypoxia, in pathophysiology, e.g. inflammation, or pharmacology, e.g. prolyl hydroxylase inhibitors.

Submissions will undergo a regular review process.

Submission deadline: May 1, 2024

Editor: Dr. Joachim Fandrey, Institute for Physiology, University of Duisburg-Essen, Germany