GeroScience - Editor's Pick

Marco Malavolta, Italian Institute for Health and Science of Aging, Italy

Areas of expertise: Animal disease models, Clinical and Translational Studies, Gerontology and Geriatric Medicine

He is a researcher in the Advanced Technology Center in Aging Research at IRCCS INRCA, the Italian Institute for Health and Science of Aging (Ancona, Italy). His research interests lie in the field of Biogerontology and Geroscience. He is currently focused on the development and validation of treatments (mostly targeting senescent cells, such as senolytics) that can ameliorate frailty and extend health and lifespan in geriatric mice.

Editor's Pick: Free to read/Open Access

Kiss, T., Nyúl-Tóth, Á., DelFavero, J. et al. Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. (2022)  https://doi.org/10.1007/s11357-022-00521-7 (this opens in a new tab)  (FREE access until November 20th)

Brunt, V.E., LaRocca, T.J., Bazzoni, A.E. et al. The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging  (2021)  https://doi.org/10.1007/s11357-020-00257-2 (this opens in a new tab)  (FREE access until November 20th)

Karin, O., Alon, U. Senescent cell accumulation mechanisms inferred from parabiosis (2021) https://doi.org/10.1007/s11357-020-00286-x (this opens in a new tab)   (Open Access)

Raj, K., Szladovits, B., Haghani, A. et al. Epigenetic clock and methylation studies in cats (2021) https://doi.org/10.1007/s11357-021-00445-8 (this opens in a new tab)   (Open Access)

Li, X., McPherson, M., Hager, M. et al. Four anti-aging drugs and calorie-restricted diet produce parallel effects in fat, brain, muscle, macrophages, and plasma of young mice (2023) https://doi.org/10.1007/s11357-023-00770-0 (this opens in a new tab)   (FREE access until November 20th)