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Overview

Journal of Pharmacokinetics and Pharmacodynamics is a comprehensive resource covering all aspects of pharmacokinetics, pharmacodynamics, and the application of pharmacometrics to drug development and clinical care.

  • Includes physiological-based pharmacokinetics (PBPK), and systems pharmacology (QSP).
  • Presents both theoretical and experimental papers on a range of related topics.
  • Considers applications of machine learning to pharmacokinetics-pharmacodynamics.
  • Applies research findings to real-world observations.
  • Official journal of the International Society of Pharmacometrics (ISoP).

Editor-in-Chief
  • Peter Bonate
Impact factor
2.5 (2022)
5 year impact factor
2.4 (2022)
Submission to first decision (median)
8 days
Downloads
285,145 (2023)

Latest articles

Journal updates

  • In Memoriam: Hartmut Derendorf

    The journal extends its condolences to the family of Editorial Advisory Board Member Hartmut Derendorf, who unexpectedly passed away on November 23, 2020.  He was a leader in the field and he contributed to the journal as a reviewer and author.  A commentary on his life and legacy was published in March 2021. His obituary can be found here.

  • Journal of Pharmacokinetics and Pharmacodynamics Special Issue on Chronopharmacometrics

    Chronopharmacology is part of pharmacology that is concerned with effects of biological rhythms while pharmacometrics relates to mathematical models of pharmacokinetics and pharmacodynamics of drugs. Chronopharmacometrics encompasses pharmacometric methods relevant to quantifying chronopharmacology and chronotherapeutics. 

    A special issue of Journal of Pharmacokinetics and Pharmacodynamics on Chronopharmacometrics was published in July 2021 presenting state-of-the-art modeling approaches that address the presence of biorhythms in biomarkers used in drug development and therapeutics. Potential topics included but were not limited to:

    • Examples of drugs and biomarkers exhibiting biorhythms: genes, hormones, cells, physiological processes
    • Cosinor analysis and other statistical approaches to detecting and quantifying rhythms in physiological baselines
    • PKPD, PBPK, QSP models of drugs and drug effects with circadian rhythms
    • Mixed effects models of biorhythmic data
    • Time to event analysis of sleep/awake patterns
    • Optimization of dosing regimens for drugs with circadian PKPD
    • Machine learning methods for identification and quantification of biorhythms
    • Real-time data collection of digital data and biorhythms
    • Models of biorhythms in cell cycle
    • Examples of software designed for analysis of biorhythmic data 

Journal information

Electronic ISSN
1573-8744
Print ISSN
1567-567X
Abstracted and indexed in
  1. ANVUR
  2. BFI List
  3. BIOSIS
  4. Baidu
  5. Biological Abstracts
  6. CLOCKSS
  7. CNKI
  8. CNPIEC
  9. Chemical Abstracts Service (CAS)
  10. Chimica
  11. Current Contents/Life Sciences
  12. Dimensions
  13. EBSCO
  14. EMBASE
  15. Google Scholar
  16. Japanese Science and Technology Agency (JST)
  17. Medline
  18. Meta
  19. Naver
  20. OCLC WorldCat Discovery Service
  21. Portico
  22. ProQuest
  23. Reaxys
  24. SCImago
  25. SCOPUS
  26. Science Citation Index Expanded (SCIE)
  27. TD Net Discovery Service
  28. UGC-CARE List (India)
  29. Wanfang
Copyright information

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